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器官提取物与精神病学的发展:1923年至1938年莫兹利医院的激素治疗

Organ extracts and the development of psychiatry: hormonal treatments at the Maudsley Hospital 1923-1938.

作者信息

Evans Bonnie, Jones Edgar

出版信息

J Hist Behav Sci. 2012 Summer;48(3):251-76. doi: 10.1002/jhbs.21548. Epub 2012 May 29.

DOI:10.1002/jhbs.21548
PMID:22644956
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3594693/
Abstract

The use of organ extracts to treat psychiatric disorder in the interwar period is an episode in the history of psychiatry which has largely been forgotten. An analysis of case-notes from The Maudsley Hospital from the period 1923-1938 shows that the prescription of extracts taken from animal testes, ovaries, thyroids, and other organs was widespread within this London Hospital. This article explores the way in which Maudsley doctors justified these treatments by tying together psychological theories of the unconscious with experimental data drawn from laboratory studies of human organs. It explores the logic behind these treatments and examines beliefs about their efficacy. The connection between this historical episode and current research in endocrinology and psychology is explored.

摘要

两次世界大战之间的时期,使用器官提取物治疗精神疾病是精神病学史上一段基本被遗忘的插曲。对1923年至1938年期间莫兹利医院病例记录的分析表明,从动物睾丸、卵巢、甲状腺和其他器官提取的提取物的处方在这家伦敦医院内广泛存在。本文探讨了莫兹利医院的医生通过将无意识的心理学理论与从人体器官实验室研究中得出的实验数据联系起来,为这些治疗方法辩护的方式。它探讨了这些治疗背后的逻辑,并审视了关于其疗效的信念。还探讨了这一历史事件与当前内分泌学和心理学研究之间的联系。

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The origins of mental health-oriented neuroscience in Britain.英国以心理健康为导向的神经科学的起源。
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NORMAL AND MORBID CONDITIONS OF THE TESTES FROM BIRTH TO OLD AGE IN ONE HUNDRED ASYLUM AND HOSPITAL CASES.一百例收容所及医院病例中睾丸从出生到老年的正常及病态情况
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