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重型脑损伤患者亲属的抑郁、焦虑及生活质量:急性期

Depression, anxiety and quality-of-life among relatives of patients with severe brain injury: the acute phase.

作者信息

Norup Anne, Welling Karen-Lise, Qvist Jesper, Siert Lars, Mortensen Erik L

机构信息

Department of Neurorehabilitation, Traumatic Brain Injury Unit, Copenhagen University Hospital, Glostrup, Denmark.

出版信息

Brain Inj. 2012;26(10):1192-200. doi: 10.3109/02699052.2012.672790. Epub 2012 May 30.

DOI:10.3109/02699052.2012.672790
PMID:22646665
Abstract

PRIMARY OBJECTIVE

To investigate the emotional well-being of relatives of patients with a severe brain injury in the acute setting, as well as risk factors associated with high anxiety and depression scores and impaired quality-of-life.

RESEARCH DESIGN

Clinical convenience sample.

METHODS AND PROCEDURES

Participants included 45 relatives of patients with severe brain injury recruited at a NICU. All relatives completed selected scales from the SCL-90-R and SF-36 ∼ 14 days after injury. Data concerning the condition of the patient were also collected.

MAIN OUTCOME AND RESULTS

Of the relatives, 51% and 69% reported anxiety and depression, respectively, as well as significantly impaired quality-of-life compared to normal reference populations. Regression analysis revealed that up to 20% of the variance in depression and anxiety scores could be explained by the CRASH 2 Mortality prediction.

CONCLUSIONS

The majority of the relatives had severely impaired quality-of-life and symptoms of anxiety and depression during the patient's NICU stay. Future research is required to explore stressors and evaluate effects of psychological intervention in the acute setting.

摘要

主要目标

调查急性重症脑损伤患者亲属的情绪健康状况,以及与高焦虑和抑郁评分及生活质量受损相关的危险因素。

研究设计

临床便利样本。

方法与步骤

参与者包括在新生儿重症监护病房(NICU)招募的45名重症脑损伤患者的亲属。所有亲属在受伤后约14天完成了症状自评量表(SCL-90-R)和健康调查简表(SF-36)的部分量表。还收集了有关患者病情的数据。

主要结果

亲属中分别有51%和69%报告有焦虑和抑郁,与正常参考人群相比,生活质量也显著受损。回归分析显示,抑郁和焦虑评分中高达20%的变异可由CRASH 2死亡率预测来解释。

结论

在患者入住NICU期间,大多数亲属的生活质量严重受损,并有焦虑和抑郁症状。未来需要开展研究以探索应激源,并评估急性环境中心理干预的效果。

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