抗蠕虫药物作用模式的研究：用于探究蠕虫生化特性的工具。

Studies of the mode of action of anthelmintic drugs: tools to investigate the biochemical peculiarities of helminths.

作者信息

Vanden Bossche H

机构信息

Department of Comparative Biochemistry, Janssen Research Foundation, Beerse, Belgium.

出版信息

Ann Parasitol Hum Comp. 1990;65 Suppl 1:99-102. doi: 10.1051/parasite/1990651099.

DOI:10.1051/parasite/1990651099

PMID:2264693

Abstract

An overview is given of the results from mode of action studies which improved our knowledge of some biochemical and/or electrophysiological aspects of parasitic helminths. Studies of the molecular mechanism of action of for example, antimonials, piperazine, levamisole, ivermectin, salicylanilides, praziquantel, benzimidazole carbamates, oxamniquine and hycanthone offered tools to learn more of the parasites and their hosts.

摘要

本文概述了作用方式研究的结果，这些研究增进了我们对寄生蠕虫某些生化和/或电生理方面的了解。例如，对锑剂、哌嗪、左旋咪唑、伊维菌素、水杨酰苯胺、吡喹酮、苯并咪唑氨基甲酸盐、奥沙尼喹和海恩酮作用的分子机制研究，为更多地了解寄生虫及其宿主提供了工具。