Department of Gastroenterology, Shaare Zedek Medical Center, Digestive Disease Institute, Affiliated with the Hebrew University School of Medicine, Jerusalem, Israel.
Psychol Health. 2012;27(12):1463-79. doi: 10.1080/08870446.2012.691169. Epub 2012 May 30.
Inflammatory Bowel Disease (IBD) impacts quality of life (QoL). Psychological factors influence the course of the disease and should be targeted for intervention.
Our study was a prospective, randomised control trial. Fifty-six outpatients were randomly chosen and allocated to a treatment group or a waiting-list control group. Treatment group patients attended three relaxation-training sessions and received an audio disc for home practice. Evaluations performed pre and post-treatment: state anxiety was assessed with the State-Trait Anxiety Inventory, QoL with the IBD Questionnaire. The Visual Analogue Scale assessed pain, depression, stress and mood. Patients completed a symptom monitoring diary. The control group's symptoms were monitored without study-related treatment.
Thirty-nine subjects completed the study and were included in the data analysis. Following the relaxation-training intervention, the treatment group's (n = 18) measured results showed a statistically significant improvement as compared to the control group (n = 21) (time by treatment interaction): anxiety levels decreased (p < 0.01), QoL and mood improved (p < 0.05), while levels of pain and stress decreased (p < 0.01).
Findings indicate IBD patients may benefit from relaxation training in their holistic care. New studies as well as further investigation of the subject are warranted.
炎症性肠病(IBD)会影响生活质量(QoL)。心理因素会影响疾病的进程,应作为干预的目标。
我们的研究是一项前瞻性、随机对照试验。随机选择了 56 名门诊患者,并将他们分配到治疗组或等待名单对照组。治疗组患者参加了三次放松训练课程,并获得了一张家庭练习的音频光盘。在治疗前后进行评估:状态焦虑用状态-特质焦虑量表评估,生活质量用 IBD 问卷评估。视觉模拟量表评估疼痛、抑郁、压力和情绪。患者完成症状监测日记。对照组的症状在没有研究相关治疗的情况下进行监测。
39 名受试者完成了研究并纳入数据分析。与对照组(n=21)相比,放松训练干预后,治疗组(n=18)的测量结果显示出统计学上的显著改善(时间与治疗的交互作用):焦虑水平下降(p<0.01),生活质量和情绪改善(p<0.05),而疼痛和压力水平下降(p<0.01)。
这些发现表明,IBD 患者可能会从整体护理中的放松训练中受益。需要进行新的研究以及对该主题的进一步调查。