Loukil Inès, Mallouch Nadia, Hachicha Firas, Bhiri Rim, Hijazi Ahmad, Jeddi Blouza Amel
CHU La Rabta, université Tunis El Manar, faculté de médecine de Tunis, service d'ophtalmologie, Tunis, Tunisie.
Presse Med. 2012 Dec;41(12 Pt 1):e594-8. doi: 10.1016/j.lpm.2012.02.047. Epub 2012 May 28.
To evaluate the clinical features and fundus fluorescein angiography findings of Takayasu retinopathy.
A retrospective, descriptive study of 11 patients with proven Takayasu arteritis and ischemic retinopathy examined at the Department of Ophthalmology of Rabta hospital (Tunisia). All patients underwent a complete ophthalmic examination and fluorescein angiography. Systemic corticotherapy and immunosuppressive therapy was prescribed in all patients. Green laser photocoagulation was performed in cases with ischemic retinopathy.
The mean follow-up period was 64.2 months (range, 8-82 months). The mean age at diagnosis of ischemic retinopathy was 27.9 years (range, 21-39 years). The male-to-female ratio was 0.1. We observed all stages of Takayasu's retinopathy. The best-corrected visual acuity ranged from 4/10 to 10/10. Clinical improvement was notes in 54.5 of all cases. Blindness occurs in only one case with severe ischemic retinopathy.
The ischemic retinopathy in Takayasu disease is due to a severe hypoperfusion of the retinal artery. A careful and regular clinical and angiographic monitoring must be performed to prevent blindness.
评估高安视网膜病变的临床特征和眼底荧光血管造影表现。
对拉卜塔医院（突尼斯）眼科检查的11例确诊为高安动脉炎和缺血性视网膜病变的患者进行回顾性描述性研究。所有患者均接受了全面的眼科检查和荧光血管造影。所有患者均接受了全身皮质类固醇治疗和免疫抑制治疗。对缺血性视网膜病变患者进行了绿色激光光凝治疗。
平均随访期为64.2个月（范围8 - 82个月）。缺血性视网膜病变诊断时的平均年龄为27.9岁（范围21 - 39岁）。男女比例为0.1。我们观察到了高安视网膜病变的各个阶段。最佳矫正视力范围为4/10至10/10。所有病例中有54.5%出现临床改善。仅1例严重缺血性视网膜病变患者失明。
高安病中的缺血性视网膜病变是由于视网膜动脉严重灌注不足所致。必须进行仔细且定期的临床和血管造影监测以预防失明。
