Ogata S, Uhthoff H K
Department of Orthopaedic Surgery, Chiba University, Japan.
Arthroscopy. 1990;6(4):315-21. doi: 10.1016/0749-8063(90)90063-j.
An embryologic study about the development of the human knee joint cavity was carried out with special attention to the formation of synovial plicae, using a total of 116 knees of embryos and fetuses. The incidence of synovial plicae in the fetal stage was also investigated. Formation of joint space starts at the middle of the interzone at around 8 weeks of gestation. Multiple small cavitations around the femoral condyle and patella coalesce to form larger cavitations. At around 10 1/2 weeks, the knee joint consists of a single cavity with synovial lining. At certain sites, such as at the medial part of patello-femoral and the infrapatellar regions, mesenchymal tissue strands remain. They may become plica. In the fetal stage from 11 to 20 weeks, an infrapatellar plica was found in 50% of specimens, a suprapatellar plica in 33%, and a mediopatellar plica in 37%. Only the infrapatellar plica showed a decrease in incidence.
开展了一项关于人类膝关节腔发育的胚胎学研究，特别关注滑膜皱襞的形成，共使用了116个胚胎和胎儿的膝关节。还研究了胎儿期滑膜皱襞的发生率。关节间隙在妊娠约8周时于中间带中部开始形成。股骨髁和髌骨周围的多个小腔隙融合形成更大的腔隙。在约10.5周时，膝关节由一个带有滑膜衬里的单一腔隙组成。在某些部位，如髌股内侧和髌下区域，间充质组织条索留存。它们可能会变成皱襞。在11至20周的胎儿期，50%的标本中发现有髌下皱襞，33%有髌上皱襞，37%有髌内侧皱襞。只有髌下皱襞的发生率有所下降。
