Maier H, Seitz H K, Mayer B, Adler D, Mall G, Born I A
Universitäts-HNO-Klinik Heidelberg.
Laryngorhinootologie. 1990 Nov;69(11):600-4. doi: 10.1055/s-2007-998261.
The effect of chronic ethanol consumption on the morphology of the rat parotid gland was investigated. After feeding an ethanol diet containing 36% of total calories as ethanol for 90 days light microscopic and electron microscopic investigations of the parotid gland tissue showed a striking fat accumulation compared to control rats. Besides interstitial fat tissue dispositions, fat droplets of various size occurred in most of the acinar cells. Additional morphometric investigations revealed a decrease in mean acinar cell volume (-21.9% p greater than 0.001). The latter finding reflects an atrophy of the secretory parenchyma and appears to be responsible for the impaired saliva secretion after chronic ethanol consumption which has been observed in former studies.
研究了长期摄入乙醇对大鼠腮腺形态的影响。以含36%总热量乙醇的乙醇饲料喂养大鼠90天后，对腮腺组织进行光镜和电镜检查，结果显示与对照大鼠相比，腮腺有明显的脂肪堆积。除了间质脂肪组织分布外，大多数腺泡细胞中出现了大小各异的脂滴。进一步的形态计量学研究显示，腺泡细胞平均体积减小（-21.9%，p>0.001）。后一发现反映了分泌实质的萎缩，这似乎是先前研究中观察到的长期摄入乙醇后唾液分泌受损的原因。
