Szepetiuk Grégory, Lesuisse Marianne, Piérard Gérald E, Quatresooz Pascale, Piérard-Franchimont Claudine
Department of Dermatology, Regional Hospital Citadelle, University Hospital of Liège, Liège, Belgium.
Case Rep Dermatol. 2012 Jan;4(1):80-4. doi: 10.1159/000337894. Epub 2012 Mar 30.
Both interstitial granulomatous dermatitis (IGD) and palisaded neutrophilic granulomatous dermatitis (PNGD) are rare disorders typically associated with systemic autoimmune conditions. They probably represent different aspects of a disease spectrum encompassing the concept of autoimmunity-related granulomatous dermatitis (ARGD).
A 61-year-old woman presented with ARGD and autoimmune hepatitis. The clinical presentation suggested PNGD, while histopathology was consistent with IGD.
The association of ARGD with autoimmune hepatitis is apparently a rare event. The present case shows that the clinicopathological correlation in ARGD does not always clearly fit with the classical presentations of IGD or PNGD.
间质性肉芽肿性皮炎（IGD）和栅栏状中性粒细胞肉芽肿性皮炎（PNGD）均为罕见疾病，通常与全身性自身免疫性疾病相关。它们可能代表了疾病谱的不同方面，涵盖了自身免疫性相关肉芽肿性皮炎（ARGD）的概念。
一名61岁女性患有ARGD和自身免疫性肝炎。临床表现提示为PNGD，而组织病理学结果与IGD一致。
ARGD与自身免疫性肝炎的关联显然是罕见事件。本病例表明，ARGD的临床病理相关性并不总是与IGD或PNGD的经典表现完全相符。
