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简单方法测量果蝇对刺激的行为反应，并利用这些方法来表征一个新的突变体。

Simple ways to measure behavioral responses of Drosophila to stimuli and use of these methods to characterize a novel mutant.

机构信息

Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.

出版信息

PLoS One. 2012;7(5):e37495. doi: 10.1371/journal.pone.0037495. Epub 2012 May 23.

DOI:10.1371/journal.pone.0037495
PMID:22649531
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3359294/
Abstract

The behavioral responses of adult Drosophila fruit flies to a variety of sensory stimuli--light, volatile and non-volatile chemicals, temperature, humidity, gravity, and sound--have been measured by others previously. Some of those assays are rather complex; a review of them is presented in the Discussion. Our objective here has been to find out how to measure the behavior of adult Drosophila fruit flies by methods that are inexpensive and easy to carry out. These new assays have now been used here to characterize a novel mutant that fails to be attracted or repelled by a variety of sensory stimuli even though it is motile.

摘要

先前已有研究测量过成年果蝇对各种感觉刺激（光、挥发性和非挥发性化学物质、温度、湿度、重力和声音）的行为反应。其中一些测定方法相当复杂，在讨论部分对其进行了综述。我们的目标是找到一种通过既经济又易于实施的方法来测量成年果蝇的行为。这些新的测定方法已被用于鉴定一种新型的突变体，尽管它是运动的，但对各种感觉刺激既不吸引也不排斥。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95fe/3359294/4fe55ea188dd/pone.0037495.g019.jpg
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