Chesnut Cameron, Kim Jenny
Division of Dermatology, David Geffen School of Medicine at UCLA, V A Greater Los Angeles Healthcare System, 52-121 CHS, Los Angeles, CA 90095, USA.
J Skin Cancer. 2012;2012:480985. doi: 10.1155/2012/480985. Epub 2012 May 9.
Basal cell carcinoma (BCC) is the most common human malignancy. Both epidemiological and direct evidence have established ultraviolet (UV) exposure from the sun as the most important risk factor for BCC development. There has only been one randomized and controlled study to examine sunscreen's role in the prevention of BCC, and no significant protective benefit was found. This study did not address four important concepts: sunscreen abuse, sunscreen misuse, sunscreen formulation, and cumulative UV exposure. Thus, the results of this study are difficult to interpret and extrapolate with real-world sunscreen practices.
基底细胞癌(BCC)是人类最常见的恶性肿瘤。流行病学证据和直接证据均已证实,来自太阳的紫外线(UV)照射是基底细胞癌发生的最重要风险因素。仅有一项随机对照研究探讨了防晒霜在预防基底细胞癌中的作用,但未发现显著的保护益处。该研究未涉及四个重要概念:防晒霜滥用、防晒霜误用、防晒霜配方和紫外线累积暴露。因此,这项研究的结果难以根据实际的防晒霜使用情况进行解读和推断。