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使用防晒霜与基底细胞癌真的没有益处吗?对相关文献的批判性综述以及新防晒霜标签规定在实际防晒霜使用中的应用。

Is there truly no benefit with sunscreen use and Basal cell carcinoma? A critical review of the literature and the application of new sunscreen labeling rules to real-world sunscreen practices.

作者信息

Chesnut Cameron, Kim Jenny

机构信息

Division of Dermatology, David Geffen School of Medicine at UCLA, V A Greater Los Angeles Healthcare System, 52-121 CHS, Los Angeles, CA 90095, USA.

出版信息

J Skin Cancer. 2012;2012:480985. doi: 10.1155/2012/480985. Epub 2012 May 9.

Abstract

Basal cell carcinoma (BCC) is the most common human malignancy. Both epidemiological and direct evidence have established ultraviolet (UV) exposure from the sun as the most important risk factor for BCC development. There has only been one randomized and controlled study to examine sunscreen's role in the prevention of BCC, and no significant protective benefit was found. This study did not address four important concepts: sunscreen abuse, sunscreen misuse, sunscreen formulation, and cumulative UV exposure. Thus, the results of this study are difficult to interpret and extrapolate with real-world sunscreen practices.

摘要

基底细胞癌(BCC)是人类最常见的恶性肿瘤。流行病学证据和直接证据均已证实,来自太阳的紫外线(UV)照射是基底细胞癌发生的最重要风险因素。仅有一项随机对照研究探讨了防晒霜在预防基底细胞癌中的作用,但未发现显著的保护益处。该研究未涉及四个重要概念:防晒霜滥用、防晒霜误用、防晒霜配方和紫外线累积暴露。因此,这项研究的结果难以根据实际的防晒霜使用情况进行解读和推断。

相似文献

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Sunscreen abuse for intentional sun exposure.防晒霜滥用导致的故意日晒。
Br J Dermatol. 2009 Nov;161 Suppl 3:40-5. doi: 10.1111/j.1365-2133.2009.09448.x.
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UV-induced immune suppression and sunscreen.紫外线诱导的免疫抑制与防晒霜
Photodermatol Photoimmunol Photomed. 2000 Jun;16(3):101-10. doi: 10.1034/j.1600-0781.2000.d01-14.x.

本文引用的文献

2
Sunscreen abuse for intentional sun exposure.防晒霜滥用导致的故意日晒。
Br J Dermatol. 2009 Nov;161 Suppl 3:40-5. doi: 10.1111/j.1365-2133.2009.09448.x.
5
Prolonged prevention of squamous cell carcinoma of the skin by regular sunscreen use.通过定期使用防晒霜长期预防皮肤鳞状细胞癌。
Cancer Epidemiol Biomarkers Prev. 2006 Dec;15(12):2546-8. doi: 10.1158/1055-9965.EPI-06-0352. Epub 2006 Nov 28.
10
The epidemiology of UV induced skin cancer.紫外线诱导的皮肤癌的流行病学。
J Photochem Photobiol B. 2001 Oct;63(1-3):8-18. doi: 10.1016/s1011-1344(01)00198-1.

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