Shen Wen-Wu, Chen Juan, Deng Jia-Hui, Zhuo Yu, Fan Yu, Kuang Wei-Hong
Mental Health Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 Mar;43(2):297-9.
To study the occurrence and characteristics of hypokalemia to the patients with acute and severe mental disorders, and analyze its influencing factors.
There were 815 patients with actue and severe mental disorder admitted into our psychiatry department from June 2009 to May 2010, who all received the examination of potassium concentration routinely at the admission. The patients were divided into hypokalemia group and non-hypokalemia group, and the clinical information were surveyed and compared between the two groups to find out the influencing factors of hypokalemia.
There were 177 patients with hypokalemia, and the proportion was 21.72%. Between the two groups, the difference of age, sex, admission season, whether with physical diseases and diagnosis were statistically significant (P < 0.05), while spiritual movement situation was not significant different (P > 0.05). Spearman rank correlation analysis showed that the incidence of hypokalemia was negatively correlated with age (r = -0.55, P = 0.00). Furthermore, multivariate analysis found that women, poor diet and physical disease were risk factors of hypolalemia (P < 0.05).
There is relatively high probability of hypokalemia occurrence to the patients with acute and severe mental disorders, which should be distinguished and treated at the admission timely.
探讨急性重症精神障碍患者低钾血症的发生情况及特点，并分析其影响因素。
选取2009年6月至2010年5月在我院精神科住院的815例急性重症精神障碍患者，均于入院时常规检测血钾浓度。将患者分为低钾血症组和非低钾血症组，对两组患者的临床资料进行调查并比较，以找出低钾血症的影响因素。
低钾血症患者177例，占21.72%。两组患者在年龄、性别、入院季节、是否伴有躯体疾病及诊断方面差异有统计学意义（P<0.05），而精神运动情况差异无统计学意义（P>0.05）。Spearman等级相关分析显示，低钾血症的发生率与年龄呈负相关（r=-0.55，P=0.00）。进一步多因素分析发现，女性、饮食差及躯体疾病是低钾血症的危险因素（P<0.05）。
急性重症精神障碍患者发生低钾血症的概率较高，入院时应及时甄别并处理。
