儿童和青少年糖尿病患者的心血管疾病：我们现在在哪里，我们要去哪里？
Cardiovascular disease in children and adolescents with diabetes: where are we, and where are we going?
机构信息
Department of Pediatrics, The Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado 80045, USA.
出版信息
Diabetes Technol Ther. 2012 Jun;14 Suppl 1(Suppl 1):S11-21. doi: 10.1089/dia.2012.0018.
Abstract
The increasing prevalence of type 1 and type 2 diabetes mellitus combined with advancement in early detection of cardiovascular disease (CVD) has placed CVD as a significant concern for preventative pediatric medicine. The public health burden of type 2 diabetes is predicted to parallel increasing obesity in children with a projected increase of early CVD in adulthood. In this article, we review practice guidelines for cardiovascular health in children and adolescents with diabetes and data on which they are based. We then focus on imaging modalities that are promising tools to expand our understanding of the cardiovascular risk imposed on youths with diabetes.
摘要
1 型和 2 型糖尿病的患病率不断上升，加上心血管疾病 (CVD) 的早期检测技术不断进步，使得 CVD 成为儿科预防医学的一个重要关注点。预计儿童 2 型糖尿病的公共卫生负担将与儿童肥胖症的增加成正比，预计成年人早期 CVD 的发病率也会增加。本文综述了糖尿病患儿心血管健康的临床实践指南及其依据的数据，然后重点介绍了一些有前途的成像方式，这些方式可以帮助我们更好地了解糖尿病青少年所面临的心血管风险。
相似文献
1
Cardiovascular disease in children and adolescents with diabetes: where are we, and where are we going?儿童和青少年糖尿病患者的心血管疾病：我们现在在哪里，我们要去哪里？
Diabetes Technol Ther. 2012 Jun;14 Suppl 1(Suppl 1):S11-21. doi: 10.1089/dia.2012.0018.
2
Prevalence of cardiovascular risk factors in children and adolescents with type 1 diabetes in Austria.奥地利 1 型糖尿病患儿和青少年心血管危险因素的流行情况。
Eur J Pediatr. 2012 Aug;171(8):1193-202. doi: 10.1007/s00431-012-1704-x. Epub 2012 Mar 16.
3
Burden of Cardiovascular Risk Factors Over Time and Arterial Stiffness in Youth With Type 1 Diabetes Mellitus: The SEARCH for Diabetes in Youth Study.心血管危险因素随时间变化的负担与 1 型糖尿病青少年的动脉僵硬度：青少年糖尿病研究（SEARCH）。
J Am Heart Assoc. 2019 Jul 2;8(13):e010150. doi: 10.1161/JAHA.118.010150. Epub 2019 Jun 19.
4
Cardiovascular disease in diabetes type 2: current concepts.2 型糖尿病中的心血管疾病：当前概念。
J Intern Med. 2018 Sep;284(3):240-253. doi: 10.1111/joim.12804. Epub 2018 Jul 18.
5
The Problem of Abnormal Body Weight and Dyslipidemia as Risk Factors for Cardiovascular Diseases in Children and Adolescents with Type 1 Diabetes.超重和血脂异常问题作为 1 型糖尿病患儿和青少年心血管疾病的危险因素。
J Diabetes Res. 2021 Aug 2;2021:5555149. doi: 10.1155/2021/5555149. eCollection 2021.
6
[A critical appraisal of the European guidelines on diabetes, pre-diabetes and cardiovascular diseases].[对欧洲糖尿病、糖尿病前期和心血管疾病指南的批判性评估]
G Ital Cardiol (Rome). 2014 Jun;15(6):350-4. doi: 10.1714/1582.17276.
7
[Not Available].[无可用内容]。
Ther Umsch. 2017;74(8):445-453. doi: 10.1024/0040-5930/a000939.
8
Diabetes: glycated hemoglobin is a marker of diabetes and CVD risk.糖尿病：糖化血红蛋白是糖尿病和心血管疾病风险的标志物。
Nat Rev Cardiol. 2010 Jul;7(7):367-8. doi: 10.1038/nrcardio.2010.84.
9
Cardiovascular disease (CVD) limbo: how soon and low should we go to prevent CVD in diabetes?心血管疾病（CVD）困境：为预防糖尿病患者的心血管疾病，我们应多快且将目标降至多低？
Diabetes Technol Ther. 2012 Jun;14(6):449-52. doi: 10.1089/dia.2012.0078. Epub 2012 Apr 3.
10
A Pilot Study of School-Based Comprehensive Cardiovascular Screening in Middle School Children.一项针对中学生的基于学校的综合心血管筛查的初步研究。
J Pediatr. 2019 May;208:287-289. doi: 10.1016/j.jpeds.2019.01.034. Epub 2019 Mar 15.
引用本文的文献
1
Sex-Related Differences in Cardiovascular Disease Risk Profile in Children and Adolescents with Type 1 Diabetes.性别相关差异在 1 型糖尿病患儿和青少年心血管疾病风险特征中的表现。
Int J Mol Sci. 2021 Sep 22;22(19):10192. doi: 10.3390/ijms221910192.
2
CARDEA study protocol: investigating early markers of cardiovascular disease and their association with lifestyle habits, inflammation and oxidative stress in adolescence using a cross-sectional comparison of adolescents with type 1 diabetes and healthy controls.CARDEA 研究方案：使用 1 型糖尿病青少年与健康对照的横断面比较，研究心血管疾病的早期标志物及其与生活方式习惯、炎症和氧化应激的关系。
BMJ Open. 2021 Sep 8;11(9):e046585. doi: 10.1136/bmjopen-2020-046585.
3
Two-Dimensional Speckle Tracking Versus Applanation Tonometry in Evaluation of Subclinical Atherosclerosis in Children with Type 1 Diabetes Mellitus.二维斑点追踪与压平眼压测量在评价 1 型糖尿病患儿亚临床动脉粥样硬化中的比较。
Med Sci Monit. 2019 Sep 28;25:7289-7294. doi: 10.12659/MSM.916466.
4
Associations between lead concentrations and cardiovascular risk factors in U.S. adolescents.美国青少年体内铅浓度与心血管危险因素之间的关联。
Sci Rep. 2017 Aug 22;7(1):9121. doi: 10.1038/s41598-017-09701-4.
5
Glycemic variability predicts inflammation in adolescents with type 1 diabetes.血糖变异性可预测1型糖尿病青少年的炎症反应。
J Pediatr Endocrinol Metab. 2016 Oct 1;29(10):1129-1133. doi: 10.1515/jpem-2016-0139.
6
Development, initial content validation and reliability of Nigerian composite lifestyle CVD risk factors questionnaire for adolescents.尼日利亚青少年心血管疾病复合生活方式风险因素问卷的编制、初始内容效度及信度
Afr Health Sci. 2014 Sep;14(3):600-8. doi: 10.4314/ahs.v14i3.15.
7
Current knowledge and future directions on cardiovascular disease in diabetes.糖尿病心血管疾病的当前认知与未来方向
Diabetes Technol Ther. 2012 Jun;14 Suppl 1(Suppl 1):S75-6. doi: 10.1089/dia.2012.0106.
本文引用的文献
1
A new insight of mechanisms, diagnosis and treatment of diabetic cardiomyopathy.糖尿病心肌病的发病机制、诊断和治疗的新见解。
Endocrine. 2012 Jun;41(3):398-409. doi: 10.1007/s12020-012-9623-1. Epub 2012 Feb 10.
2
What matters in ADVANCE and ADVANCE-ON.ADVANCE 和 ADVANCE-ON 中的要点。
Diabetes Obes Metab. 2012 Jan;14 Suppl 1:20-9. doi: 10.1111/j.1463-1326.2011.01509.x.
3
Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report.儿童和青少年心血管健康与风险降低综合指南专家小组：总结报告
Pediatrics. 2011 Dec;128 Suppl 5(Suppl 5):S213-56. doi: 10.1542/peds.2009-2107C. Epub 2011 Nov 14.
4
Clinical implications of the ACCORD trial.ACCORD 试验的临床意义。
J Clin Endocrinol Metab. 2012 Jan;97(1):41-8. doi: 10.1210/jc.2011-1679. Epub 2011 Nov 2.
5
Myocardial structure, function, and scar in patients with type 1 diabetes mellitus.1 型糖尿病患者的心肌结构、功能和瘢痕。
Circulation. 2011 Oct 18;124(16):1737-46. doi: 10.1161/CIRCULATIONAHA.111.022327. Epub 2011 Sep 26.
6
Childhood obesity and cardiovascular disease: links and prevention strategies.儿童肥胖与心血管疾病：关联与预防策略。
Nat Rev Cardiol. 2011 Jun 14;8(9):513-25. doi: 10.1038/nrcardio.2011.86.
7
Blood pressure targets in diabetes: is this the time for change?糖尿病患者的血压目标：是时候做出改变了吗？
J Clin Hypertens (Greenwich). 2011 Apr;13(4):258-62. doi: 10.1111/j.1751-7176.2011.00430.x.
8
Macrovascular angiopathy in children and adolescents with type 1 diabetes.1 型糖尿病患儿和青少年的大血管血管病变。
Diabetes Metab Res Rev. 2011 Jul;27(5):436-60. doi: 10.1002/dmrr.1195.
9
Endothelial dysfunction is related to poor glycemic control in adolescents with type 1 diabetes under 5 years of disease: evidence of metabolic memory.内皮功能障碍与 5 年内发病的 1 型糖尿病青少年血糖控制不佳有关：代谢记忆的证据。
J Clin Endocrinol Metab. 2011 May;96(5):1493-9. doi: 10.1210/jc.2010-2363. Epub 2011 Feb 23.
10
Cardiovascular function/dysfunction in adolescents with type 1 diabetes.青少年 1 型糖尿病患者的心血管功能/障碍。
Curr Diab Rep. 2011 Jun;11(3):185-92. doi: 10.1007/s11892-011-0180-4.
Zotero 插件