Centro Superior de Investigacion en Salud Publica (CSISP), Area de Investigación en Vacunas, Avda Catalunya 21, Valencia 46020, Spain.
BMC Pediatr. 2012 May 31;12:58. doi: 10.1186/1471-2431-12-58.
Rotavirus (RV) is the commonest cause of acute gastroenteritis in infants and young children worldwide. A Quality of Life study was conducted in primary care in three European countries as part of a larger epidemiological study (SPRIK) to investigate the impact of paediatric rotavirus gastroenteritis (RVGE) on affected children and their parents.
A self-administered questionnaire was linguistically validated in Spanish, Italian and Polish. The questionnaire was included in an observational multicentre prospective study of 302 children aged <5 years presenting to a general practitioner or paediatrician for RVGE at centres in Spain, Italy or Poland. RV infection was confirmed by polymerase chain reaction (PCR) testing (n = 264). The questionnaire was validated and used to assess the emotional impact of paediatric RVGE on the parents.
Questionnaire responses showed that acute RVGE in a child adversely affects the parents' daily life as well as the child. Parents of children with RVGE experience worry, distress and impact on their daily activities. RVGE of greater clinical severity (assessed by the Vesikari scale) was associated with higher parental worries due to symptoms and greater changes in the child's behaviour, and a trend to higher impact on parents' daily activities and higher parental distress, together with a higher score on the symptom severity scale of the questionnaire.
Parents of a child with acute RVGE presenting to primary care experience worry, distress and disruptions to daily life as a result of the child's illness. Prevention of this disease through prophylactic vaccination will improve the daily lives of parents and children.
轮状病毒（RV）是全世界婴幼儿急性胃肠炎的最常见病因。作为一项更大规模的流行病学研究（SPRIK）的一部分，在三个欧洲国家的初级保健中进行了一项生活质量研究，以调查小儿轮状病毒胃肠炎（RVGE）对受影响儿童及其父母的影响。
在西班牙语、意大利语和波兰语中对自我管理问卷进行了语言验证。该问卷包含在一项针对西班牙、意大利或波兰中心因 RVGE 就诊于全科医生或儿科医生的 302 名<5 岁儿童的观察性多中心前瞻性研究中。通过聚合酶链反应（PCR）检测（n = 264）确认 RV 感染。对问卷进行了验证，并用于评估小儿 RVGE 对父母的情绪影响。
问卷回答显示，儿童急性 RVGE 会对父母的日常生活以及儿童产生不良影响。RVGE 患儿的父母会感到担忧、痛苦并影响其日常活动。临床严重程度较高（根据 Vesikari 量表评估）的 RVGE 与症状引起的父母担忧增加以及儿童行为变化更大有关，父母日常活动受到更大影响和父母痛苦增加的趋势，以及问卷症状严重程度量表的评分较高。
因急性 RVGE 就诊于初级保健的儿童的父母会因孩子的疾病而感到担忧、痛苦和日常生活受到干扰。通过预防性疫苗接种预防这种疾病将改善父母和孩子的日常生活。
