Department of Paediatrics, Hvidovre Hospital, University of Copenhagen, Kettegaard Alle 30, 2650 Hvidovre, Denmark.
Eur J Pediatr. 2011 Dec;170(12):1535-9. doi: 10.1007/s00431-011-1465-y. Epub 2011 Apr 16.
This was the first study to characterize the total burden of rotavirus gastroenteritis (RVGE) at both hospital and general physician (GP) clinics in Denmark, and also the first to confirm rotavirus (RV) as the leading cause of acute gastroenteritis (GE) among children <5 years in GP clinics nationwide. Several aspects of RVGE were reported, including the impact of RVGE on family life by changes in HRQoL and by the number of days absent from day care. RV was detected in 225 (63.6%) children, and the median number of days absent from day care was 5 days. In 43.0% of the families, at least one family member, a total of 170 individuals, experienced symptoms of acute GE. Reduced health-related quality of life was observed both among children and parents. Our data suggested that RVGE indirectly as well as directly is a major public health burden in Denmark and comparable with data from other European countries.
这是首次在丹麦的医院和全科医生（GP）诊所中全面描述轮状病毒肠胃炎（RVGE）负担的研究，也是首次确认轮状病毒（RV）是全国 GP 诊所中 5 岁以下儿童急性肠胃炎（GE）的主要病因。报告了 RVGE 的多个方面，包括 RVGE 通过改变 HRQoL 和日托缺勤天数对家庭生活的影响。在 225 名（63.6%）儿童中检测到 RV，日托缺勤中位数为 5 天。在 43.0%的家庭中，共有 170 人至少有一名家庭成员出现急性 GE 症状。儿童和父母的健康相关生活质量均有所下降。我们的数据表明，RVGE 无论是直接还是间接，都是丹麦的一个主要公共卫生负担，与来自其他欧洲国家的数据相当。
