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1 型糖尿病的低碳水化合物饮食:长期改善和依从性:临床审计。

Low carbohydrate diet in type 1 diabetes, long-term improvement and adherence: A clinical audit.

机构信息

Formerly Department of Medicine, Blekingesjukhuset, Karlshamn, 37480, Karlshamn, Sweden.

出版信息

Diabetol Metab Syndr. 2012 May 31;4(1):23. doi: 10.1186/1758-5996-4-23.

Abstract

BACKGROUND

Reduction of dietary carbohydrates and corresponding insulin doses stabilizes and lowers mean blood glucose in individuals with type 1 diabetes within days. The long-term adherence for persons who have learned this technique is unknown. To assess adherence over 4 years in such a group the present audit was done retrospectively by record analysis for individuals who have attended an educational course. Adherence was assessed from HbA1c changes and individuals' own reports.

FINDINGS

Altogether 48 persons with diabetes duration of 24 ± 12 years and HbA1c > = 6.1% (Mono-S; DCCT = 7.1%) attended the course. Mean HbA1c for all attendees was at start, at 3 months and 4 years 7.6% ± 1.0%, 6.3 ± 0.7%, 6.9 ± 1.0% respectively. The number of non-adherent persons was 25 (52%). HbA1c in this group was at start, at 3 months and 4 years: 7.5 ±1.1%, 6.5 ± 0.8%, 7.4 ± 0.9%. In the group of 23 (48%) adherent persons mean HbA1c was at start, at 3 months and 4 years 7.7 ± 1.0%, 6.4 ± 0.9%, 6.4 ± 0.8%.

CONCLUSION

Attending an educational course on dietary carbohydrate reduction and corresponding insulin reduction in type 1 diabetes gave lasting improvement. About half of the individuals adhered to the program after 4 years. The method may be useful in informed and motivated persons with type 1 diabetes. The number needed to treat to have lasting effect in 1 was 2.

摘要

背景

减少饮食中的碳水化合物和相应的胰岛素剂量可以在几天内稳定并降低 1 型糖尿病患者的平均血糖。但是,对于已经掌握了这种技术的人来说,长期坚持这种方法的情况并不清楚。为了评估在这样的人群中 4 年以上的依从性,我们对参加过教育课程的个体进行了回顾性记录分析。依从性通过 HbA1c 的变化和个体的自我报告进行评估。

结果

共有 48 名糖尿病病程 24±12 年且 HbA1c≥6.1%(Mono-S;DCCT=7.1%)的患者参加了该课程。所有参加者的平均 HbA1c 在开始时、3 个月和 4 年后分别为 7.6%±1.0%、6.3±0.7%和 6.9±1.0%。不依从的人数为 25 人(52%)。该组患者的 HbA1c 在开始时、3 个月和 4 年后分别为 7.5±1.1%、6.5±0.8%和 7.4±0.9%。在 23 名(48%)依从患者中,平均 HbA1c 在开始时、3 个月和 4 年后分别为 7.7±1.0%、6.4±0.9%和 6.4±0.8%。

结论

参加 1 型糖尿病饮食中碳水化合物减少和相应胰岛素减少的教育课程可带来持久的改善。大约一半的患者在 4 年后仍坚持该方案。该方法可能对 1 型糖尿病中知情且积极配合的患者有用。需要治疗的人数为 2。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7124/3583262/3d7d1b6012e9/1758-5996-4-23-1.jpg

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