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先天性心脏病手术成人患者的早期拔管。

Early extubation in adults undergoing surgery for congenital heart disease.

机构信息

Division of Pediatric Cardiology, Yale University School of Medicine, New Haven, CT, USA.

出版信息

J Cardiothorac Vasc Anesth. 2012 Oct;26(5):773-6. doi: 10.1053/j.jvca.2012.04.009. Epub 2012 May 30.

Abstract

OBJECTIVES

Early extubation in adults undergoing surgery for congenital heart disease has not been described. The authors report their experience with extubation in the operating room (OR), including factors associated with the decision to defer extubation to a later time.

DESIGN

A retrospective chart review.

SETTING

A tertiary-care teaching hospital.

PARTICIPANTS

This study included adults undergoing surgery for congenital heart disease using cardiopulmonary bypass. Exclusion criteria were as follows: preoperative mechanical ventilation, age >70 years, inotrope score >20 after surgery, and surgical risk (Risk Adjustment for Congenital Heart Surgery [RACHS] score ≥4).

INTERVENTIONS

A stepwise logistic regression model was used to test for the independent influence of the various factors on extubation in the OR.

MEASUREMENTS AND MAIN RESULTS

Sixty-seven patients (age 18-59 years, median = 32 years) were included. Overall, 79% of patients were extubated in the OR. The RACHS score was the strongest predictor of deferring extubation (RACHS 3 v 1 or 2: odds ratio = 16.7; 95% confidence interval, 3.3-84.2; p = 0.0006). Further exploration of the high-risk group (RACHS 3) showed that 75% of the RACHS 3 patients with a body mass index <25 were extubated compared with only 20% of patients who had a body mass index ≥25 (p = 0.01). Other factors included in the analysis did not contribute any additional independent information.

CONCLUSIONS

Extubation of adult patients in the OR after surgery for congenital heart disease is feasible in most cases. Surgical risk (RACHS score) and body mass index predict the decision for OR extubation in this patient population.

摘要

目的

成人先天性心脏病手术中早期拔管尚未有报道。作者报告了他们在手术室(OR)中进行拔管的经验,包括与决定将拔管推迟到更晚时间相关的因素。

设计

回顾性图表审查。

地点

一家三级保健教学医院。

参与者

本研究纳入了使用体外循环行先天性心脏病手术的成年人。排除标准如下:术前机械通气、年龄>70 岁、术后儿茶酚胺评分>20、手术风险(先天性心脏病手术风险调整 [RACHS] 评分≥4)。

干预

采用逐步逻辑回归模型检验各种因素对 OR 中拔管的独立影响。

测量和主要结果

共纳入 67 例患者(年龄 18-59 岁,中位数=32 岁)。总体而言,79%的患者在 OR 中拔管。RACHS 评分是预测推迟拔管的最强因素(RACHS 3 与 1 或 2:优势比=16.7;95%置信区间,3.3-84.2;p=0.0006)。对高危组(RACHS 3)的进一步探索表明,75%的 BMI<25 的 RACHS 3 患者在 OR 中拔管,而 BMI≥25 的患者只有 20%(p=0.01)。分析中纳入的其他因素没有提供任何额外的独立信息。

结论

在大多数情况下,成人先天性心脏病手术后在 OR 中拔管是可行的。手术风险(RACHS 评分)和体重指数预测了该患者人群在 OR 中拔管的决策。

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