Division of Dermatology, University of California-San Diego, CA 92123, USA.
Dermatitis. 2012 Jan-Feb;23(1):17-21. doi: 10.1097/DER.0b013e31823d191f.
Although allergic contact dermatitis of the eyelids is a common condition, limited information is available regarding the selection of patch-testing chemicals for proper evaluation.
The purpose of this analysis was to evaluate the relevance of allergens responsible for allergic eyelid dermatitis among a series of patch-tested patients attending our clinic at the University of Miami and compare these results to published studies in the literature.
Data were retrospectively reviewed for eyelid-only dermatitis from clinically relevant patch-test evaluations performed between December 2004 and January 2007.
Formaldehyde was the most frequently encountered antigen, accounting for 45.83% (11/24) of the cases, followed by nickel 33.33% (8/24) and balsam of Peru (Myroxylon pereirae) 29.17% (7/24). In addition, not only did we find a higher prevalence of certain allergens when compared with other studies, but we identified several relevant allergens not previously reported at other referral centers.
The allergens found to be relevant in eyelid dermatitis vary among different regions. These data may help contribute to generating a standard screening tool to improve the detection and management of these cases.
尽管眼睑过敏性接触性皮炎是一种常见疾病,但对于适当评估的斑贴试验化学物质选择,相关信息有限。
本分析旨在评估在迈阿密大学诊所接受斑贴试验的一系列患者中,引起过敏性眼睑皮炎的过敏原的相关性,并将这些结果与文献中的已发表研究进行比较。
回顾性分析了 2004 年 12 月至 2007 年 1 月期间进行的具有临床相关性的斑贴试验评估中仅涉及眼睑的皮炎数据。
甲醛是最常遇到的抗原,占 45.83%(11/24),其次是镍 33.33%(8/24)和秘鲁香脂(Myroxylon pereirae)29.17%(7/24)。此外,我们不仅发现与其他研究相比,某些过敏原的患病率更高,而且还发现了一些以前在其他转诊中心未报告过的相关过敏原。
在不同地区发现的与眼睑皮炎相关的过敏原有所不同。这些数据可能有助于生成标准的筛选工具,以提高这些病例的检测和管理水平。