Hamsch C, Hadaschik E
Universitäts-Hautklinik Heidelberg, Voßstr. 2, 69115, Heidelberg, Deutschland.
Hautarzt. 2012 Jun;63(6):487-9. doi: 10.1007/s00105-012-2394-z.
Focal, mostly suprabasal acantholyis with development of dyskeratotic keratinocytes are typical histological features of Grover's disease. The histological distinction between other forms of acantholytic dermatoses is often difficult. A combined assessment of the histological findings and the clinical symptoms often allows a clear diagnosis. The disease is self-limiting but treatment is necessary in some cases due to the sometimes excessive pruritis.
局灶性、主要位于基底层上方的棘层松解伴角化不良角质形成细胞形成是格罗弗病典型的组织学特征。区分其他形式的棘层松解性皮肤病的组织学表现往往很困难。组织学检查结果与临床症状相结合的评估通常有助于明确诊断。该病具有自限性，但由于有时瘙痒过度，在某些情况下仍需治疗。
