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运动过程中骨骼肌 FAT/CD36 的双重作用机制。

A dual mechanism of action for skeletal muscle FAT/CD36 during exercise.

机构信息

Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.

出版信息

Exerc Sport Sci Rev. 2012 Oct;40(4):211-7. doi: 10.1097/JES.0b013e31825eb263.

DOI:10.1097/JES.0b013e31825eb263
PMID:22653277
Abstract

Carnitine palmitoyltransferase I has been viewed historically as the sole regulator of fatty acid oxidation. However, we have identified fatty acid translocase/CD36 as an additional control point. Specifically, fatty acid translocase/CD36 seems to have a novel dual mechanism of action with regard to fatty acid oxidation during exercise, influencing transport of lipids across the sarcolemmal membrane and into the mitochondria.

摘要

肉毒碱棕榈酰基转移酶 I 一直被视为脂肪酸氧化的唯一调节物。然而,我们已经确定脂肪酸转运蛋白/CD36 是另一个控制节点。具体而言,脂肪酸转运蛋白/CD36 似乎在运动过程中对脂肪酸氧化具有新颖的双重作用机制,影响脂质穿过肌膜并进入线粒体的转运。

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A dual mechanism of action for skeletal muscle FAT/CD36 during exercise.运动过程中骨骼肌 FAT/CD36 的双重作用机制。
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Contribution of FAT/CD36 to the regulation of skeletal muscle fatty acid oxidation: an overview.FAT/CD36对骨骼肌脂肪酸氧化调节的作用:综述
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