人胎盘转铁蛋白受体的分离与鉴定
Isolation and characterization of the transferrin receptor from human placenta.
作者信息
Seligman P A, Schleicher R B, Allen R H
出版信息
J Biol Chem. 1979 Oct 25;254(20):9943-6.
PMID:226547
Abstract
The transferrin receptor has been isolated from human placenta using immunochromatography and affinity chromatography. The receptor is a glycoprotein and has a Mr = 90,000 on sodium dodecyl sulfate-gel electrophoresis in the presence of 2-mercaptoethanol. The isolated receptor is immunologically related to the transferrin receptor on the reticulocyte cell surface.
摘要
已使用免疫色谱法和亲和色谱法从人胎盘中分离出转铁蛋白受体。该受体是一种糖蛋白，在存在2-巯基乙醇的情况下，经十二烷基硫酸钠-凝胶电泳测定其分子量为90,000。分离出的受体与网织红细胞细胞表面的转铁蛋白受体在免疫学上相关。
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