Kikukawa Ryuji, Kimura Junpei, Nasu Tetsuo, Sasaki Motoki, Fukuta Katsuhiro, Yasuda Masahiro
Department of Veterinary Anatomy, Faculty of Agriculture, University of Miyazaki, Japan.
Vet Immunol Immunopathol. 2012 Sep 15;149(1-2):103-7. doi: 10.1016/j.vetimm.2012.05.010. Epub 2012 May 15.
Tragulidae is a primitive ungulate family within the order Cetartiodactyla, suborder Ruminantia. Domestic ruminants such as cattle, sheep, and goat have two types of Peyer's patches (PP): jejunal and ileal PP, in which there are morphological and functional differences. In this study, lesser mouse deer (Tragulus javanicus) PP was studied by gross anatomical and histological procedures. At the fetal stage, both types of PP were formed in the small intestine. Ileal PP was observed as a single continuous aggregation of lymphatic follicles extending cranially from the ileo-caecal junction. However, jejunal PP was observed as multiple and discrete accumulations of lymphatic follicles. This study showed that the lesser mouse deer has two types of PP in the small intestine. In addition, the anatomical and histological characteristics of jejunal and ileal PP are quite similar to those of other ruminants' jejunal and ileal PP. Further studies are needed to analyze immune function of both PP in lesser mouse deer in order to determine the evolutionary process of Cetartiodactyla.
鼷鹿科是偶蹄目、反刍亚目下的一个原始有蹄类家族。牛、羊和山羊等家养反刍动物有两种派尔集合淋巴结（PP）：空肠派尔集合淋巴结和回肠派尔集合淋巴结，它们在形态和功能上存在差异。在本研究中，通过大体解剖和组织学方法对小鼷鹿（爪哇鼷鹿）的派尔集合淋巴结进行了研究。在胎儿阶段，小肠中形成了两种类型的派尔集合淋巴结。回肠派尔集合淋巴结表现为从回盲交界处向头侧延伸的单个连续的淋巴滤泡聚集。然而，空肠派尔集合淋巴结表现为多个离散的淋巴滤泡聚集。本研究表明，小鼷鹿在小肠中有两种类型的派尔集合淋巴结。此外，空肠和回肠派尔集合淋巴结的解剖和组织学特征与其他反刍动物的空肠和回肠派尔集合淋巴结非常相似。需要进一步研究分析小鼷鹿两种派尔集合淋巴结的免疫功能，以确定偶蹄目的进化过程。
