INQUINOA-CONICET, Ayacucho 471, Tucumán 4000, Argentina.
Phytochemistry. 2012 Aug;80:115-22. doi: 10.1016/j.phytochem.2012.04.017. Epub 2012 Jun 1.
Four unusual terpenylated acylphloroglucinols were isolated from the diethyl ether extract of the scales and rhizomes of the fern Dryopteris wallichiana together with the known compounds albaspidins AA and AB, and filixic acids ABA and ABB. Structures of the isolated compounds were established by extensive spectroscopic analysis and their absolute configuration at C-14″ was determined by comparing their CD spectra with those simulated for the respective isomers. Pure acylphloroglucinols displayed moderate in vitro nematocidal activity against L4 stage larvae of Nippostrongylus brasiliensis (LD₅₀=22-121 μM).
从鳞毛蕨科植物狗脊的鳞片和根茎的乙醚提取物中分离得到了四个不寻常的萜烯酰基间苯三酚，以及已知的化合物 albaspidins AA 和 AB，以及 filixic acids ABA 和 ABB。通过广泛的光谱分析确定了分离化合物的结构，并通过将它们的 CD 光谱与各自异构体的模拟光谱进行比较来确定 C-14″的绝对构型。纯酰基间苯三酚对巴西钩虫 L4 期幼虫显示出中等体外杀线虫活性（LD₅₀=22-121 μM）。
