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妊娠期甲状腺功能。

Thyroid function in pregnancy.

机构信息

Boston University School of Medicine, Section of Endocrinology, Diabetes, and Nutrition, 88 East Newton Street, Evans 201, Boston, MA, USA.

出版信息

J Trace Elem Med Biol. 2012 Jun;26(2-3):137-40. doi: 10.1016/j.jtemb.2012.03.004. Epub 2012 Jun 2.

DOI:10.1016/j.jtemb.2012.03.004
PMID:22658718
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3990259/
Abstract

Iodine is required for the production of thyroid hormones. Normal thyroid function during pregnancy is important for both the mother and developing fetus. This review discusses the changes in thyroid physiology that occur during pregnancy, the significance of thyroid function tests and thyroid antibody titers assessed during pregnancy, and the potential obstetric complications associated with maternal hypothyroidism.

摘要

碘是甲状腺激素生成所必需的。妊娠期间甲状腺功能正常对母亲和胎儿发育都很重要。本文综述了妊娠期间甲状腺生理学的变化、妊娠期间评估的甲状腺功能试验和甲状腺自身抗体滴度的意义,以及与母体甲状腺功能减退相关的潜在产科并发症。

相似文献

1
Thyroid function in pregnancy.妊娠期甲状腺功能。
J Trace Elem Med Biol. 2012 Jun;26(2-3):137-40. doi: 10.1016/j.jtemb.2012.03.004. Epub 2012 Jun 2.
2
THE THYROID GLAND IN HUMAN REPRODUCTION.人类生殖中的甲状腺
Mod Trends Hum Reprod Physiol. 1963;15:155-74.
3
Maternal and Fetal Thyroid Physiology.母婴甲状腺生理学
Clin Obstet Gynecol. 2019 Jun;62(2):302-307. doi: 10.1097/GRF.0000000000000439.
4
[Thyroid function and pregnancy. II. Study "in vitro"].甲状腺功能与妊娠。II. “体外”研究
Rev Argent Endocrinol Metab. 1966 Sep;12(3):149-57.
5
Thyroid function in pregnancy - maternal-fetal relationship in health and disease.孕期甲状腺功能——健康与疾病中的母婴关系
Pediatr Endocrinol Rev. 2003 Dec;1 Suppl 2:170-6; discussion 176.
6
Pituitary regulation of thyroid function in pregnancy.孕期垂体对甲状腺功能的调节
Horm Metab Res. 1970 Nov;2(6):338-43. doi: 10.1055/s-0028-1095050.
7
Fetal and maternal thyroid hormones.胎儿和母体甲状腺激素。
Horm Res. 1987;26(1-4):12-27. doi: 10.1159/000180681.
8
The thyroid gland in pregnancy.孕期的甲状腺
Major Probl Obstet Gynecol. 1972;3:1-138.
9
Recommendations for thyroxin therapy during pregnancy.孕期甲状腺素治疗的建议。
Expert Opin Pharmacother. 2008 Feb;9(3):421-7. doi: 10.1517/14656566.9.3.421.
10
[The influence of iodine deficiency during pregnancy of fetal and neonatal development].孕期碘缺乏对胎儿及新生儿发育的影响
Ginekol Pol. 2001 Nov;72(11):908-16.

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J Endocrinol Invest. 2025 Aug 11. doi: 10.1007/s40618-025-02651-z.
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Medications and Food Interfering with the Bioavailability of Levothyroxine: A Systematic Review.影响左甲状腺素生物利用度的药物与食物:一项系统评价
Ther Clin Risk Manag. 2023 Jun 23;19:503-523. doi: 10.2147/TCRM.S414460. eCollection 2023.
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Levothyroxine: Conventional and Novel Drug Delivery Formulations.左甲状腺素:常规和新型药物制剂。
Endocr Rev. 2023 May 8;44(3):393-416. doi: 10.1210/endrev/bnac030.
7
Benefits of rescreening newborns of mothers affected by autoimmune hypothyroidism.对受自身免疫性甲状腺功能减退症影响的母亲所生新生儿进行再次筛查的益处。
Eur Thyroid J. 2022 Aug 5;11(5). doi: 10.1530/ETJ-22-0060. Print 2022 Oct 1.
8
Antenatal thyroid hormone therapy and antithyroid drug use in Norway from 2004 to 2018.2004年至2018年挪威的产前甲状腺激素治疗及抗甲状腺药物使用情况
Endocr Connect. 2022 Apr 29;11(4):e210631. doi: 10.1530/EC-21-0631.
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Assessment of Iodine and Selenium Nutritional Status in Women of Reproductive Age in Latvia.评估拉脱维亚育龄妇女的碘和硒营养状况。
Medicina (Kaunas). 2021 Nov 5;57(11):1211. doi: 10.3390/medicina57111211.
10
Association of Maternal Hypothyroidism With Cardiovascular Diseases in the Offspring.母亲甲状腺功能减退与后代心血管疾病的关联。
Front Endocrinol (Lausanne). 2021 Aug 31;12:739629. doi: 10.3389/fendo.2021.739629. eCollection 2021.

本文引用的文献

1
Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum.美国甲状腺协会关于妊娠期及产后甲状腺疾病诊断和管理的指南。
Thyroid. 2011 Oct;21(10):1081-125. doi: 10.1089/thy.2011.0087. Epub 2011 Jul 25.
2
Thyroid testing during pregnancy at an academic Boston Area Medical Center.在波士顿学术医疗中心的孕期甲状腺检测。
J Clin Endocrinol Metab. 2011 Sep;96(9):E1452-6. doi: 10.1210/jc.2011-0360. Epub 2011 Jun 29.
3
Effects of maternal subclinical hypothyroidism on obstetrical outcomes during early pregnancy.母孕期亚临床甲状腺功能减退对早期妊娠产科结局的影响。
J Endocrinol Invest. 2012 Mar;35(3):322-5. doi: 10.3275/7772. Epub 2011 May 31.
4
Significance of (sub)clinical thyroid dysfunction and thyroid autoimmunity before conception and in early pregnancy: a systematic review.妊娠前及孕早期(亚)临床甲状腺功能障碍和甲状腺自身免疫的意义:系统综述。
Hum Reprod Update. 2011 Sep-Oct;17(5):605-19. doi: 10.1093/humupd/dmr024. Epub 2011 May 28.
5
Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence.甲状腺自身抗体与流产和早产的关系:证据的荟萃分析。
BMJ. 2011 May 9;342:d2616. doi: 10.1136/bmj.d2616.
6
Early pregnancy reference intervals of thyroid hormone concentrations in a thyroid antibody-negative pregnant population.甲状腺自身抗体阴性的妊娠人群中甲状腺激素浓度的早孕期参考区间。
Thyroid. 2011 Mar;21(3):291-8. doi: 10.1089/thy.2010.0337. Epub 2011 Jan 22.
7
Maternal thyroid function at 11 to 13 weeks of gestation and subsequent fetal death.妊娠 11 至 13 周时的母体甲状腺功能与随后的胎儿死亡。
Thyroid. 2010 Sep;20(9):989-93. doi: 10.1089/thy.2010.0058.
8
Pregnancy outcomes in women with thyroid peroxidase antibodies.甲状腺过氧化物酶抗体阳性妇女的妊娠结局。
Obstet Gynecol. 2010 Aug;116(2 Pt 1):381-386. doi: 10.1097/AOG.0b013e3181e904e5.
9
Increased pregnancy loss rate in thyroid antibody negative women with TSH levels between 2.5 and 5.0 in the first trimester of pregnancy.在妊娠早期 TSH 水平在 2.5 至 5.0 之间的甲状腺抗体阴性女性中,妊娠丢失率增加。
J Clin Endocrinol Metab. 2010 Sep;95(9):E44-8. doi: 10.1210/jc.2010-0340. Epub 2010 Jun 9.
10
Thyroid function in women found to have early pregnancy loss.发现有早期妊娠丢失的女性的甲状腺功能。
Thyroid. 2010 Jun;20(6):633-7. doi: 10.1089/thy.2009.0323.