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汞及其化合物的毒理学。

The toxicology of mercury and its compounds.

机构信息

Norwegian University of Science and Technology, Department of Neuroscience, Trondheim, Norway.

出版信息

J Trace Elem Med Biol. 2012 Oct;26(4):215-26. doi: 10.1016/j.jtemb.2012.02.004. Epub 2012 Jun 2.

Abstract

A concentrated review on the toxicology of inorganic mercury together with an extensive review on the neurotoxicology of methylmercury is presented. The challenges of using inorganic mercury in dental amalgam are reviewed both regarding the occupational exposure and the possible health problems for the dental patients. The two remaining "mysteries" of methylmercury neurotoxicology are also being reviewed; the cellular selectivity and the delayed onset of symptoms. The relevant literature on these aspects has been discussed and some suggestions towards explaining these observations have been presented.

摘要

本文对无机汞的毒理学进行了集中综述,并对甲基汞的神经毒理学进行了广泛综述。本文回顾了在牙科汞合金中使用无机汞所面临的挑战,包括职业暴露和对牙科患者可能产生的健康问题。本文还对甲基汞神经毒理学的两个剩余“谜团”,即细胞选择性和症状迟发,进行了综述。对这些方面的相关文献进行了讨论,并提出了一些解释这些观察结果的建议。

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