Tareq Mays S, Hamad Tagreed K
Applied Science Department, University of Technology, Baghdad, Iraq.
Department of Laser and Optoelectronics Engineering, College of Engineering, Al-Nahrain University, Baghdad, Iraq.
Odontology. 2025 Mar 18. doi: 10.1007/s10266-025-01088-3.
This study used ICP-MS and LIBS techniques to assess element migration in healthy, caries-prone, and dental treatment materials in human teeth. The researchers also analyzed the accumulation of significant minerals and toxic elements in calcified tissues. The laser drilling process was monitored in vitro using spectral measurements of the ablated plasma. This study found that while non-mineralizing elements and organic materials increased in concentration, the shift from caries to healthy tooth material was distinguished by a decrease in calcium and phosphorus concentrations. The migration of elements over time, such as Al, Ba, Hg, Pb, and Sr, from dental restorative materials to the tooth matrix, can also be linked to the spatial distribution of these elements. The ICP-MS studies revealed that certain elements had moved from dental cavity fillings to the healthy area of the teeth. These analyses reveal high/low element concentrations inside the tooth matrix, allowing monitoring of mineralization of the hydroxyapatite matrix and element migration, as well as identification of disease states like dental caries.
本研究使用电感耦合等离子体质谱（ICP-MS）和激光诱导击穿光谱（LIBS）技术来评估人体牙齿中健康、易患龋齿和牙科治疗材料中的元素迁移。研究人员还分析了钙化组织中重要矿物质和有毒元素的积累情况。使用烧蚀等离子体的光谱测量在体外监测激光钻孔过程。本研究发现，虽然非矿化元素和有机材料的浓度增加，但从龋齿到健康牙齿材料的转变表现为钙和磷浓度的降低。随着时间的推移，诸如铝（Al）、钡（Ba）、汞（Hg）、铅（Pb）和锶（Sr）等元素从牙科修复材料向牙基质的迁移，也与这些元素的空间分布有关。ICP-MS研究表明，某些元素已从牙腔填充物迁移至牙齿的健康区域。这些分析揭示了牙基质内元素浓度的高/低情况，从而能够监测羟基磷灰石基质的矿化和元素迁移，以及识别诸如龋齿等疾病状态。
