Department of Environmental Medicine and Infectious Diseases, Kyushu University, Fukuoka, Japan.
J Atheroscler Thromb. 2012;19(5):462-70. doi: 10.5551/jat.11528. Epub 2012 Jan 31.
A simple, non-invasive medical device, using bioelectrical impedance analysis (BIA) for the evaluation of visceral fat level (VFL) was developed recently. The aim of this study was to investigate the utility of VFL by BIA in the screening of metabolic syndrome (MetS).
VFL was measured by the BIA device in 1,451 Japanese residents (546 men and 905 women, age range 30-69 years).
VFL had significant positive correlations with waist circumference (WC) and body mass index (r=0.772 and 0.849, all P < 0.0001). The overall MetS prevalence using Japanese Diagnosis Criteria was 19.8%: men 36.3% and women 9.8%. The mean VFL of the participants with MetS was significantly higher than those without MetS (men; 12.1 and 9.4, women; 13.3 and 8.7) (both P < 0.001). VFL significantly correlated with blood pressure, lipid profiles, fasting plasma glucose, and hemoglobin A1c (all P < 0.001). Receiver operating characteristic curve analysis for a diagnosis of two or more MetS risk factors excluding WC resulted in the same cutoff values for the VFL (10.0) of men and women.
The VFL by BIA is useful for the detection of MetS because it is correlated with all metabolic parameters and shows the same normal limit in both sexes.
最近开发了一种使用生物电阻抗分析（BIA）评估内脏脂肪水平（VFL）的简单、无创的医疗设备。本研究旨在探讨 BIA 测量 VFL 在代谢综合征（MetS）筛查中的应用价值。
使用 BIA 设备测量了 1451 名日本居民（546 名男性和 905 名女性，年龄 30-69 岁）的 VFL。
VFL 与腰围（WC）和体重指数（BMI）呈显著正相关（r=0.772 和 0.849，均 P < 0.0001）。使用日本诊断标准，总体 MetS 患病率为 19.8%：男性 36.3%，女性 9.8%。患有 MetS 的参与者的平均 VFL 明显高于没有 MetS 的参与者（男性分别为 12.1 和 9.4，女性分别为 13.3 和 8.7）（均 P < 0.001）。VFL 与血压、血脂谱、空腹血糖和糖化血红蛋白（HbA1c）显著相关（均 P < 0.001）。排除 WC 后用于诊断两个或更多 MetS 危险因素的 ROC 曲线分析得出了相同的男性和女性 VFL（10.0）截断值。
BIA 测量的 VFL 对于 MetS 的检测是有用的，因为它与所有代谢参数相关，并且在两性中显示出相同的正常范围。
