Popescu Ștefana-Oana, Mihai Andreea, Turcu-Știolică Adina, Lupu Carmen Elena, Cismaru Diana-Maria, Grecu Victor Ionel, Scafa-Udriște Alexandru, Ene Răzvan, Mititelu Magdalena
Department of Biochemistry, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Municipal Hospital Orșova, 225200 Orșova, Romania.
Nutrients. 2025 Mar 14;17(6):1024. doi: 10.3390/nu17061024.
: This study examines the relationship between visceral fat (VF), metabolic health, and dietary patterns in patients with obstructive bronchial diseases (OBDs) using bioelectrical impedance analysis (BIA). : A total of 75 patients diagnosed with OBD, including chronic obstructive pulmonary disease (COPD) and/or asthma, were assessed for VF levels via BIA. Dietary habits were evaluated using a structured questionnaire to explore their correlation with VF accumulation. : The study cohort comprised predominantly male participants (66.7%), with the majority aged between 61 and 70 years (46.7%). Significant gender differences in VF distribution were observed, with 60% of females maintaining normal VF levels (1-9) compared to only 28% of males, while 38% of males exhibited very high VF levels (15-30; = 0.003). Body mass index (BMI) showed a strong correlation with VF ( < 0.0001), as overweight and obese individuals predominantly displayed elevated VF levels (≥10). Moreover, metabolic syndrome (MS) was present in 66.7% of participants, with these individuals exhibiting significantly higher VF levels compared to those without MS ( = 0.001). Dietary analysis revealed that frequent consumption of fast food (r = 0.717, < 0.001), carbonated drinks (r = 0.366, = 0.001), and refined carbohydrates (r = 0.438, < 0.001) was significantly associated with increased VF accumulation. Conversely, higher intake of water (r = -0.551, < 0.001), fruits (r = -0.581, < 0.001), and vegetables (r = -0.482, < 0.001) correlated with lower VF levels. Lack of physical activity was also strongly linked to VF accumulation (r = 0.481, < 0.001), further reinforcing the role of lifestyle factors in metabolic health. : The findings underscore the significant impact of dietary habits and physical activity on VF accumulation in OBD patients. BMI and MS emerged as critical predictors of VF, while unhealthy dietary patterns and sedentary lifestyles further exacerbated VF deposition. Elevated VF levels were linked to adverse lipid profiles, reinforcing the need for dietary and lifestyle modifications in managing metabolic health among OBD patients. Although no direct association was identified between VF and forced expiratory volume in one second (FEV1), the results highlight the necessity of integrated nutritional and metabolic interventions in the management of chronic respiratory diseases.
本研究采用生物电阻抗分析(BIA),探讨阻塞性支气管疾病(OBD)患者内脏脂肪(VF)、代谢健康与饮食模式之间的关系。
共有75例被诊断为OBD(包括慢性阻塞性肺疾病(COPD)和/或哮喘)的患者通过BIA评估VF水平。使用结构化问卷评估饮食习惯,以探讨其与VF积累的相关性。
研究队列主要由男性参与者(66.7%)组成,大多数年龄在61至70岁之间(46.7%)。观察到VF分布存在显著性别差异,60%的女性保持正常VF水平(1 - 9),而男性仅为28%,38%的男性表现出非常高的VF水平(15 - 30;P = 0.003)。体重指数(BMI)与VF呈强相关(P < 0.0001),超重和肥胖个体主要表现出升高的VF水平(≥10)。此外,66.7%的参与者存在代谢综合征(MS),这些个体的VF水平显著高于无MS者(P = 0.001)。饮食分析显示,经常食用快餐(r = 0.717,P < 0.001)、碳酸饮料(r = 0.366,P = 0.001)和精制碳水化合物(r = 0.438,P < 0.001)与VF积累增加显著相关。相反,较高的水摄入量(r = -0.551,P < 0.001)、水果摄入量(r = -0.581,P < 0.001)和蔬菜摄入量(r = -0.482,P < 0.001)与较低的VF水平相关。缺乏体育活动也与VF积累密切相关(r = 0.481,P < 0.001),进一步强化了生活方式因素在代谢健康中的作用。
研究结果强调了饮食习惯和体育活动对OBD患者VF积累的重大影响。BMI和MS是VF的关键预测因素,而不健康的饮食模式和久坐的生活方式进一步加剧了VF沉积。升高的VF水平与不良血脂谱相关,这凸显了在OBD患者代谢健康管理中进行饮食和生活方式调整的必要性。尽管未发现VF与一秒用力呼气量(FEV1)之间存在直接关联,但结果强调了在慢性呼吸道疾病管理中进行综合营养和代谢干预的必要性。