Department of Pediatrics, University of Illinois College of Medicine at Rockford, Rockford, Illinois, USA.
Pediatrics. 2012 Jul;130(1):e220-3. doi: 10.1542/peds.2011-1200. Epub 2012 Jun 4.
Adolescents with well-controlled cystic fibrosis, including good lung function and appropriate growth, commonly participate in competitive athletic activities. We present the case of an adolescent male with cystic fibrosis, hyponatremia, dehydration, and rhabdomyolysis after participating in football practice on a summer morning. The patient presented with severe myalgia and serum sodium of 129 mmol/L, chloride 90 mmol/L, and creatine phosphokinase 1146 U/L. Aggressive hydration with intravenous 0.9% saline resulted in clinical improvement with no renal or muscular sequelae. Health care providers need to educate patients with cystic fibrosis about maintaining adequate hydration and sodium repletion during exercise. Research is needed regarding the appropriate amount and composition of oral rehydration fluids in exercising individuals with cystic fibrosis, as the physiology encountered in these patients provides a unique challenge to maintaining electrolyte balance and stimulation of thirst.
患有囊性纤维化且病情控制良好的青少年，包括肺功能良好和生长发育正常，通常会参与竞技体育活动。我们报告了 1 例囊性纤维化青少年患者的病例，该患者在夏季的一个早晨参加足球训练后出现低钠血症、脱水和横纹肌溶解。患者表现出严重的肌肉疼痛，血清钠 129mmol/L、氯 90mmol/L 和肌酸磷酸激酶 1146U/L。静脉输注 0.9%生理盐水进行积极水化治疗后，临床症状改善，无肾脏或肌肉后遗症。医务人员需要教育囊性纤维化患者，让他们了解在运动期间保持充足的水合和钠补充的重要性。对于运动中的囊性纤维化患者，需要进行有关口服补液液的适当量和成分的研究，因为这些患者的生理学为维持电解质平衡和刺激口渴带来了独特的挑战。
