Suppr超能文献

创伤性脑损伤、小胶质细胞与β淀粉样蛋白

Traumatic brain injury, microglia, and Beta amyloid.

作者信息

Mannix Rebekah C, Whalen Michael J

机构信息

Division of Emergency Medicine, Department of Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA 02124, USA.

出版信息

Int J Alzheimers Dis. 2012;2012:608732. doi: 10.1155/2012/608732. Epub 2012 May 14.

Abstract

Recently, there has been growing interest in the association between traumatic brain injury (TBI) and Alzheimer's Disease (AD). TBI and AD share many pathologic features including chronic inflammation and the accumulation of beta amyloid (Aβ). Data from both AD and TBI studies suggest that microglia play a central role in Aβ accumulation after TBI. This paper focuses on the current research on the role of microglia response to Aβ after TBI.

摘要

最近,创伤性脑损伤(TBI)与阿尔茨海默病(AD)之间的关联越来越受到关注。TBI和AD具有许多病理特征,包括慢性炎症和β淀粉样蛋白(Aβ)的积累。来自AD和TBI研究的数据表明,小胶质细胞在TBI后的Aβ积累中起核心作用。本文重点关注目前关于TBI后小胶质细胞对Aβ反应作用的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68d5/3359797/1580193c92bc/IJAD2012-608732.001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验