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[实体器官移植后的肺部感染]

[Pulmonary infections following solid organ transplantation].

作者信息

Müller Veronika, Kováts Zsuzsanna, Horváth Gábor

机构信息

Semmelweis Egyetem, Általános Orvostudományi Kar Pulmonológiai Klinika, Budapest.

出版信息

Orv Hetil. 2012 Jun 10;153(23):899-903. doi: 10.1556/OH.2012.29395.

Abstract

Solid organ transplantation is the standard of care for selected patients with severe vital organ dysfunction. The need for immunosuppression to prevent organ rejection is a common characteristic of recipients. Immunosuppression increases the risk of infections, especially with low virulence opportunistic pathogens. Infections following solid organ transplantation mainly affect the lungs and the airways. Establishing the diagnosis includes a wide spectrum of pulmonary diagnostics, high standard microbiological analysis and various imaging methods. With the improvement of treatment options, the number of kidney, liver, heart and lung transplant recipients is increasing and, therefore, more and more physicians may meet pulmonary complications in these patients.

摘要

实体器官移植是某些患有严重重要器官功能障碍患者的标准治疗方法。接受者的一个共同特征是需要免疫抑制来预防器官排斥。免疫抑制会增加感染风险,尤其是低毒力机会性病原体感染。实体器官移植后的感染主要影响肺部和气道。确立诊断包括广泛的肺部诊断、高标准的微生物学分析和各种成像方法。随着治疗选择的改善,肾、肝、心和肺移植受者的数量在增加,因此,越来越多的医生可能会遇到这些患者的肺部并发症。

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