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纽约大学转化听觉研究实验室当前及计划中的人工耳蜗研究。

Current and planned cochlear implant research at New York University Laboratory for Translational Auditory Research.

作者信息

Svirsky Mario A, Fitzgerald Matthew B, Neuman Arlene, Sagi Elad, Tan Chin-Tuan, Ketten Darlene, Martin Brett

机构信息

Department of Otolaryngology, New York University, New York, NY 10016, USA.

出版信息

J Am Acad Audiol. 2012 Jun;23(6):422-37. doi: 10.3766/jaaa.23.6.5.

DOI:10.3766/jaaa.23.6.5
PMID:22668763
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3677062/
Abstract

The Laboratory of Translational Auditory Research (LTAR/NYUSM) is part of the Department of Otolaryngology at the New York University School of Medicine and has close ties to the New York University Cochlear Implant Center. LTAR investigators have expertise in multiple related disciplines including speech and hearing science, audiology, engineering, and physiology. The lines of research in the laboratory deal mostly with speech perception by hearing impaired listeners, and particularly those who use cochlear implants (CIs) or hearing aids (HAs). Although the laboratory's research interests are diverse, there are common threads that permeate and tie all of its work. In particular, a strong interest in translational research underlies even the most basic studies carried out in the laboratory. Another important element is the development of engineering and computational tools, which range from mathematical models of speech perception to software and hardware that bypass clinical speech processors and stimulate cochlear implants directly, to novel ways of analyzing clinical outcomes data. If the appropriate tool to conduct an important experiment does not exist, we may work to develop it, either in house or in collaboration with academic or industrial partners. Another notable characteristic of the laboratory is its interdisciplinary nature where, for example, an audiologist and an engineer might work closely to develop an approach that would not have been feasible if each had worked singly on the project. Similarly, investigators with expertise in hearing aids and cochlear implants might join forces to study how human listeners integrate information provided by a CI and a HA. The following pages provide a flavor of the diversity and the commonalities of our research interests.

摘要

转化听觉研究实验室(LTAR/NYUSM)是纽约大学医学院耳鼻咽喉科的一部分,与纽约大学人工耳蜗植入中心有着密切联系。LTAR的研究人员在多个相关学科领域拥有专业知识,包括言语和听力科学、听力学、工程学和生理学。该实验室的研究方向主要涉及听力受损听众的言语感知,尤其是那些使用人工耳蜗(CI)或助听器(HA)的听众。尽管该实验室的研究兴趣广泛,但仍有一些共同的线索贯穿并联系着其所有工作。特别是,对转化研究的浓厚兴趣是该实验室开展的即使是最基础研究的基础。另一个重要因素是工程和计算工具的开发,其范围从言语感知的数学模型到绕过临床言语处理器并直接刺激人工耳蜗的软件和硬件,再到分析临床结果数据的新方法。如果进行一项重要实验所需的合适工具不存在,我们可能会努力自行开发,或者与学术或行业合作伙伴合作开发。该实验室的另一个显著特点是其跨学科性质,例如,听力学家和工程师可能会密切合作,开发一种如果各自单独开展该项目就不可行的方法。同样,在助听器和人工耳蜗方面具有专业知识的研究人员可能会联手研究人类听众如何整合人工耳蜗和助听器提供的信息。以下页面展示了我们研究兴趣的多样性和共性。

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J Am Acad Audiol. 2012 Jun;23(6):422-37. doi: 10.3766/jaaa.23.6.5.
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引用本文的文献

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A potential neurophysiological correlate of electric-acoustic pitch matching in adult cochlear implant users: Pilot data.成年人工耳蜗使用者电-声音调匹配的潜在神经生理学关联:初步数据。
Cochlear Implants Int. 2018 Jul;19(4):198-209. doi: 10.1080/14670100.2018.1442126. Epub 2018 Mar 6.
2
Pitch Matching between Electrical Stimulation of a Cochlear Implant and Acoustic Stimuli Presented to a Contralateral Ear with Residual Hearing.人工耳蜗电刺激与向对侧有残余听力的耳朵呈现的声刺激之间的音高匹配
J Am Acad Audiol. 2017 Mar;28(3):187-199. doi: 10.3766/jaaa.15063.
3
Gradual adaptation to auditory frequency mismatch.

本文引用的文献

1
A mathematical model of medial consonant identification by cochlear implant users.人工耳蜗使用者的中置辅音识别的数学模型。
J Acoust Soc Am. 2011 Apr;129(4):2191-200. doi: 10.1121/1.3531806.
2
Speech perception in congenitally deaf children receiving cochlear implants in the first year of life.先天性耳聋儿童在生命的第一年接受人工耳蜗植入后的言语感知。
Otol Neurotol. 2010 Oct;31(8):1254-60. doi: 10.1097/MAO.0b013e3181f2f475.
3
A new software tool to optimize frequency table selection for cochlear implants.一种用于优化人工耳蜗频率表选择的新软件工具。
对听觉频率失配的逐渐适应
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4
Pitch comparisons between electrical stimulation of a cochlear implant and acoustic stimuli presented to a normal-hearing contralateral ear.人工耳蜗电刺激与正常对侧耳听到的声刺激的频率比较。
J Assoc Res Otolaryngol. 2010 Dec;11(4):625-40. doi: 10.1007/s10162-010-0222-7. Epub 2010 Jun 5.
5
Speech production intelligibility of early implanted pediatric cochlear implant users.早期植入人工耳蜗的儿童使用者的言语产生清晰度
Int J Pediatr Otorhinolaryngol. 2010 Aug;74(8):855-9. doi: 10.1016/j.ijporl.2010.04.009. Epub 2010 May 15.
6
Combined effects of noise and reverberation on speech recognition performance of normal-hearing children and adults.噪声和混响对正常听力儿童和成人言语识别性能的联合影响。
Ear Hear. 2010 Jun;31(3):336-44. doi: 10.1097/AUD.0b013e3181d3d514.
7
A mathematical model of vowel identification by users of cochlear implants.人工耳蜗使用者元音识别的数学模型。
J Acoust Soc Am. 2010 Feb;127(2):1069-83. doi: 10.1121/1.3277215.
8
Development of the North American Listening in Spatialized Noise-Sentences test (NA LiSN-S): sentence equivalence, normative data, and test-retest reliability studies.北美空间噪声中的句子听力测试(NA LiSN-S)的开发:句子等效性、常模数据及重测信度研究
J Am Acad Audiol. 2009 Feb;20(2):128-46. doi: 10.3766/jaaa.20.2.6.
9
A model of incomplete adaptation to a severely shifted frequency-to-electrode mapping by cochlear implant users.一种不完全适应严重频率-电极映射移位的耳蜗植入使用者模型。
J Assoc Res Otolaryngol. 2010 Mar;11(1):69-78. doi: 10.1007/s10162-009-0187-6. Epub 2009 Sep 23.
10
Sensitivity to interaural time difference with bilateral cochlear implants: Development over time and effect of interaural electrode spacing.双侧人工耳蜗植入对双耳时间差的敏感性:随时间的发展及双耳电极间距的影响
J Acoust Soc Am. 2009 Aug;126(2):806-15. doi: 10.1121/1.3158821.