Podoprigora G I, Zbarskiĭ A I
Med Parazitol (Mosk). 1990 Sep-Oct(5):26-30.
The current state of immunodiagnostic and immunopreventive trends in parasitology and prospects for their development are analysed. The prospects of immunodiagnosis seem to be in increased sensitivity and specificity of tests by improving the methods and using the achievements of biotechnology in the manufacturing of high quality antigenic and antibody reagents. The development of immunoprevention of parasitoses can be stimulated by further studies of the mechanisms of a protective immune response, ways of its enhancement, search for natural and design of synthetic protective antigens and elaboration of new methods of their biological transport. The importance of the studies of local immunity phenomena is stressed for the development of new effective methods of immunodiagnosis and immunoprevention of socially valuable human parasitoses.
分析了寄生虫学中免疫诊断和免疫预防趋势的现状及其发展前景。免疫诊断的前景似乎在于通过改进方法和利用生物技术在高质量抗原和抗体试剂生产方面的成果来提高检测的灵敏度和特异性。对保护性免疫反应机制、增强其反应的方法、天然保护性抗原的寻找与合成保护性抗原的设计以及其生物转运新方法的进一步研究,可以促进寄生虫病免疫预防的发展。强调了局部免疫现象研究对于开发针对具有社会价值的人类寄生虫病的新型有效免疫诊断和免疫预防方法的重要性。