Division of Environmental and Occupational Health, Institute for Biosecurity, Saint Louis University, School of Public Health, 3545 Lafayette Avenue, St. Louis, MO 63104, USA.
Infect Control Hosp Epidemiol. 2012 Jul;33(7):737-44. doi: 10.1086/666336. Epub 2012 May 10.
The 2009 pandemic H1N1 influenza vaccine had lower uptake compared to seasonal influenza vaccine, and most studies examining uptake of H1N1 vaccine focused on hospital-based healthcare personnel (HCP). Determinants of H1N1 vaccine uptake among HCP in all work settings need to be identified so that interventions can be developed for use in encouraging uptake of future pandemic or emerging infectious disease vaccines.
To identify factors influencing nonhospital HCP H1N1 influenza vaccine compliance.
An H1N1 influenza vaccine compliance questionnaire was administered to HCP working in myriad healthcare settings in March-June 2011.
Surveys were used to assess H1N1 influenza vaccine compliance and examine factors that predicted H1N1 influenza vaccine uptake.
In all, 3,188 HCP completed the survey. Hospital-based HCP had higher compliance than did non-hospital-based personnel (Χ2 = 142.2, P < .001). In logistic regression stratified by hospital setting versus nonhospital setting, determinants of H1N1 vaccination among non-hospital-based HCP included extent to which H1N1 vaccination was mandated or encouraged, perceived importance of vaccination, access to no-cost vaccine provided on-site, no fear of vaccine side effects, and trust in public health officials when they say that the influenza vaccine is safe. Determinants of hospital-based HCP H1N1 vaccine compliance included having a mandatory vaccination policy, perceived importance of vaccination, no fear of vaccine side effects, free vaccine, perceived seriousness of H1N1 influenza, and trust in public health officials.
Non-hospital-based HCP versus hospital-based HCP reasons for H1N1 vaccine uptake differed. Targeted interventions are needed to increase compliance with pandemic-related vaccines.
2009 年大流行的 H1N1 流感疫苗的接种率低于季节性流感疫苗，大多数研究 H1N1 疫苗接种的重点是基于医院的医护人员（HCP）。需要确定所有工作环境中 HCP 接种 H1N1 疫苗的决定因素，以便制定干预措施，鼓励未来大流行或新发传染病疫苗的接种。
确定影响非医院 HCP 接种 H1N1 流感疫苗的因素。
2011 年 3 月至 6 月，在各种医疗保健环境中向 HCP 发放了一份 H1N1 流感疫苗接种调查问卷。
使用调查评估 H1N1 流感疫苗接种的依从性，并研究预测 H1N1 流感疫苗接种率的因素。
共有 3188 名 HCP 完成了调查。与非医院工作人员相比，基于医院的 HCP 的疫苗接种率更高（Χ2 = 142.2，P <.001）。在按医院和非医院环境分层的逻辑回归中，非医院环境中 HCP 接种 H1N1 疫苗的决定因素包括疫苗接种是否强制或鼓励、接种疫苗的重要性、现场提供免费疫苗的机会、对疫苗副作用的恐惧、以及在公共卫生官员表示流感疫苗安全时对他们的信任。基于医院的 HCP 接种 H1N1 疫苗的决定因素包括强制接种政策、接种疫苗的重要性、对疫苗副作用的恐惧、免费疫苗、对 H1N1 流感严重性的认识以及对公共卫生官员的信任。
非医院 HCP 与医院 HCP 接种 H1N1 疫苗的原因不同。需要有针对性的干预措施来提高对大流行相关疫苗的接种率。
