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挽救性肝移植治疗肝坏疽气性菌感染。

Salvage liver transplantation for hepatic gas gangrene.

机构信息

Aix-Marseille Univ 13284 Marseille, & Assistance-Publique Hôpitaux de Marseille, Department of Digestive Surgery and Liver Transplantation, Hopital de La Conception, 13005 Marseille, France.

出版信息

J Gastrointest Surg. 2012 Sep;16(9):1802-4. doi: 10.1007/s11605-012-1917-3. Epub 2012 Jun 6.

DOI:10.1007/s11605-012-1917-3
PMID:22669442
Abstract

Hepatic gas gangrene is an uncommon situation mainly due to bacterial infection by Clostridium perfringens. It remains a life-threatening condition associated with a high mortality rate. Quick diagnosis and aggressive therapy including liver transplantation should be proposed to improve the outcome. This report describes a rare case of hepatic gas gangrene on native liver, secondary to iatrogenic hepatic artery thrombosis and instrumental biliary tree infection, which was successfully treated by liver transplantation.

摘要

肝性坏疽气肿较为少见,主要由梭状芽孢杆菌感染所致。它仍是一种危及生命的疾病,死亡率较高。快速诊断和积极治疗(包括肝移植)应被提出以改善预后。本报告描述了一例罕见的肝性坏疽气肿病例,该病例继发于医源性肝动脉血栓形成和器械性胆道树感染,通过肝移植成功治疗。

相似文献

1
Salvage liver transplantation for hepatic gas gangrene.挽救性肝移植治疗肝坏疽气性菌感染。
J Gastrointest Surg. 2012 Sep;16(9):1802-4. doi: 10.1007/s11605-012-1917-3. Epub 2012 Jun 6.
2
Hepatic gas gangrene following orthotopic liver transplantation: three cases treated with re-transplantation and a review of the literature.原位肝移植术后肝气性坏疽:3例再移植治疗及文献复习
Transpl Infect Dis. 2008 Jul;10(4):280-5. doi: 10.1111/j.1399-3062.2007.00287.x. Epub 2007 Dec 7.
3
Veno-atrial bypass for the operative treatment of septic gas gangrene secondary to delayed hepatic artery thrombosis.静脉-心房分流术用于治疗肝动脉血栓形成延迟继发的感染性气性坏疽的手术治疗
Am J Transplant. 2003 Jun;3(6):760-3. doi: 10.1034/j.1600-6143.2003.00129.x.
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Hepatic gas gangrene following liver transplantation.肝移植术后肝气体坏疽
Liver Transpl. 2007 Mar;13(3):468-9. doi: 10.1002/lt.21032.
5
Fulminant septic shock due to Clostridium perfringens skin and soft tissue infection eight years after liver transplantation.肝移植八年后因产气荚膜梭菌皮肤及软组织感染导致的暴发性脓毒性休克
Ann Transplant. 2011 Jul-Sep;16(3):143-6. doi: 10.12659/aot.882009.
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Spontaneous intrahepatic gas gangrene and fatal septic shock.自发性肝内气体坏疽与致死性感染性休克。
Acta Chir Belg. 2009 May-Jun;109(3):400-4. doi: 10.1080/00015458.2009.11680447.
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Gas gangrene secondary to Clostridium perfringens in pediatric oncology patients.儿科肿瘤患者中由产气荚膜梭菌引起的气性坏疽
Pediatr Emerg Care. 2004 Jul;20(7):457-9. doi: 10.1097/01.pec.0000132218.42729.97.
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[Gas-containing liver abscess, hepatic gas gangrene].[含气肝脓肿,肝气性坏疽]
Ryoikibetsu Shokogun Shirizu. 1995(7):36-8.
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[Gas gangrene. Apropos of 24 cases. Value of combined surgical and hyperbaric oxygen therapy].[气性坏疽。关于24例。外科手术与高压氧联合治疗的价值]
Ann Chir. 1974 Jun;28(6):445-54.
10
A comparison of the treatment of gas gangrene with and without hyperbaric oxygen.高压氧治疗与非高压氧治疗气性坏疽的比较。
Surg Gynecol Obstet. 1973 Jun;136(6):969-70.

引用本文的文献

1
Successful treatment of hepatic gas gangrene by open drainage: A case report and review of the Japanese literature.开放引流成功治疗肝气性坏疽:一例报告并复习日本文献
Int J Surg Case Rep. 2018;49:121-125. doi: 10.1016/j.ijscr.2018.06.028. Epub 2018 Jun 30.

本文引用的文献

1
Liver transplantation for severe hepatic trauma: experience from a single center.严重肝外伤的肝移植:单中心经验
World J Gastroenterol. 2009 Apr 7;15(13):1641-4. doi: 10.3748/wjg.15.1641.
2
Early hepatic artery thrombosis after liver transplantation: a systematic review of the incidence, outcome and risk factors.肝移植术后早期肝动脉血栓形成:发病率、结局及危险因素的系统评价
Am J Transplant. 2009 Apr;9(4):746-57. doi: 10.1111/j.1600-6143.2008.02541.x. Epub 2009 Mar 2.
3
Hepatic gas gangrene following orthotopic liver transplantation: three cases treated with re-transplantation and a review of the literature.
原位肝移植术后肝气性坏疽:3例再移植治疗及文献复习
Transpl Infect Dis. 2008 Jul;10(4):280-5. doi: 10.1111/j.1399-3062.2007.00287.x. Epub 2007 Dec 7.
4
Hepatic artery thrombosis following orthotopic liver transplantation: a 10-year experience from a single centre in the United Kingdom.原位肝移植术后肝动脉血栓形成:英国一家中心的10年经验
Liver Transpl. 2006 Jan;12(1):146-51. doi: 10.1002/lt.20566.
5
Hepatic artery thrombosis after adult liver transplantation.成人肝移植术后肝动脉血栓形成
Liver Transpl. 2003 Jun;9(6):612-20. doi: 10.1053/jlts.2003.50098.
6
Late hepatic artery thrombosis after orthotopic liver transplantation.原位肝移植术后晚期肝动脉血栓形成
Liver Transpl. 2003 Jun;9(6):605-11. doi: 10.1053/jlts.2003.50057.
7
Blunt liver injury: from non-operative management to liver transplantation.钝性肝损伤:从非手术治疗到肝移植
Injury. 2003 Mar;34(3):181-6. doi: 10.1016/s0020-1383(02)00283-8.
8
Delayed hepatic artery thrombosis in adult orthotopic liver transplantation-a 12-year experience.成人原位肝移植术后延迟性肝动脉血栓形成——12年经验
Transplantation. 2001 Jun 15;71(11):1592-6. doi: 10.1097/00007890-200106150-00018.
9
The role of liver transplantation in the subacute trauma patients.肝移植在亚急性创伤患者中的作用。
Am Surg. 1998 Apr;64(4):363-4.
10
Blood supply of the right and left hepatic ducts.左右肝管的血液供应。
Br J Surg. 1998 Feb;85(2):202-7. doi: 10.1046/j.1365-2168.1998.00511.x.