Rozenholc Alexandre, Abdulcadir Jasmine, Pelte Marie-Françoise, Petignat Patrick
Department of Gynecology and Obstetrics, Geneva University Hospitals, Geneva, Switzerland.
BMJ Case Rep. 2012 Jun 1;2012:bcr0120125577. doi: 10.1136/bcr.01.2012.5577.
A 24-year-old patient with 7-week amenorrhoea consulted for vaginal bleeding without abdominal pain. Ultrasonography revealed a 7 × 4 cm solid right pelvic mass. There was no visible intrauterine gestational sac. The serum β-human chorionic gonadotropin (β-hCG) level was 11 998 IU/l. Emergency laparoscopy was performed for a presumptive diagnosis of ectopic pregnancy. At laparoscopy, the right ovary was enlarged with a non-haemorrhagic 7 × 4 cm solid lesion, which was resected. The histological diagnosis was a dysgerminoma with immunohistochemistry showing nests of syncytiotrophoblastic cells, which were the origin of the hCG production. There was no pregnancy, either intrauterine or ectopic. There was no evidence of metastasis from the dysgerminoma on the positron-emission tomography scanner. The patient underwent a second procedure for surgical staging of this ovarian germ-cell tumour. This ovarian dysgerminoma was staged FIGO 1A, and the patient did not receive adjuvant therapy. There was no recurrence at the last 8-month follow-up.
一名24岁、停经7周的患者因无痛性阴道出血前来就诊。超声检查发现右侧盆腔有一个7×4厘米的实性肿块。未见宫内妊娠囊。血清β-人绒毛膜促性腺激素(β-hCG)水平为11998IU/l。因初步诊断为异位妊娠而进行了急诊腹腔镜检查。腹腔镜检查时,右侧卵巢增大,有一个7×4厘米的非出血性实性病变,予以切除。组织学诊断为无性细胞瘤,免疫组化显示合体滋养层细胞巢,这是hCG产生的来源。未发现宫内或宫外妊娠。正电子发射断层扫描仪检查未发现无性细胞瘤转移的证据。该患者接受了第二次手术,对这个卵巢生殖细胞肿瘤进行手术分期。这个卵巢无性细胞瘤分期为FIGO 1A期,患者未接受辅助治疗。在最后8个月的随访中未出现复发。