儿童特发性癫痫的认知功能
Cognitive function of idiopathic childhood epilepsy.
作者信息
You Su Jeong
机构信息
Department of Pediatrics, Epilepsy Center, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
出版信息
Korean J Pediatr. 2012 May;55(5):159-63. doi: 10.3345/kjp.2012.55.5.159. Epub 2012 May 21.
Abstract
Most children with epilepsy are of normal intelligence. However, a significant subset will have temporary or permanent cognitive impairment. Factors that affect cognitive function are myriad and include the underlying neuropathology of the epilepsy, seizures, epileptiform discharges, psychosocial problems, age at seizure onset, duration of epilepsy, and side effects associated with antiepileptic drugs. This review article discusses cognitive function in children with idiopathic epilepsy and the effects of antiepileptic drugs on cognitive function in children.
摘要
大多数癫痫患儿智力正常。然而，有相当一部分患儿会出现暂时或永久性的认知障碍。影响认知功能的因素众多，包括癫痫的潜在神经病理学、癫痫发作、癫痫样放电、心理社会问题、癫痫发作起始年龄、癫痫病程以及抗癫痫药物的副作用。这篇综述文章讨论了特发性癫痫患儿的认知功能以及抗癫痫药物对儿童认知功能的影响。
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Ther Adv Neurol Disord. 2011 Nov;4(6):385-407. doi: 10.1177/1756285611417920.
2
Neuropsychological status of children with newly diagnosed idiopathic childhood epilepsy.新诊断的特发性儿童癫痫患儿的神经心理状态
Brain Dev. 2011 Sep;33(8):666-71. doi: 10.1016/j.braindev.2010.11.003. Epub 2011 Jan 20.
3
Cognitive Effects of Low-dose Topiramate Compared with Oxcarbazepine in Epilepsy Patients.低剂量托吡酯与奥卡西平在癫痫患者中的认知影响比较。
J Clin Neurol. 2006 Jun;2(2):126-33. doi: 10.3988/jcn.2006.2.2.126. Epub 2006 Jun 20.
4
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Epilepsy Behav. 2010 Feb;17(2):193-8. doi: 10.1016/j.yebeh.2009.10.024. Epub 2009 Dec 31.
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6
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