Joint Austin-Ludwig Oncology Unit, Heidelberg, Victoria, Australia.
Australas J Dermatol. 2013 Aug;54(3):e70-3. doi: 10.1111/j.1440-0960.2012.00904.x. Epub 2012 Jun 6.
Basal cell carcinoma (BCC) is the most common human malignancy but rarely metastasises. We report on two patients with symptomatic lung metastases and a past history of recurrent BCC excisions. In our first patient, a heavy smoker with multiple lung lesions, histology of a resected nodule was first reported as non-small cell lung cancer but a repeat nodule biopsy a year later was recognised as a pulmonary metastasis from primary cutaneous BCC. Our second patient, a young never-smoker with two previous BCC, was confirmed as having a pulmonary metastasis from BCC on the lung resection specimen. Pulmonary metastasis from an unidentified primary site is a common clinical situation. These patients emphasise the importance of considering the most common cancer as a potential primary.
基底细胞癌（BCC）是最常见的人类恶性肿瘤，但很少转移。我们报告了两名有症状的肺转移患者和复发性 BCC 切除术的既往病史。在我们的第一个患者中，一个有多个肺病变的重度吸烟者，切除结节的组织学最初被报告为非小细胞肺癌，但一年后重复的结节活检被认为是原发性皮肤 BCC 的肺转移。我们的第二个患者，一个从未吸烟的年轻患者，有两次 BCC 病史，在肺切除标本上被确诊为 BCC 的肺转移。从未确定的原发灶转移到肺部是一种常见的临床情况。这些患者强调了将最常见的癌症作为潜在原发灶的重要性。
