Khosla S N
Department of Medicine, Medical College and Hospital, (Haryana), India.
Postgrad Med J. 1990 Nov;66(781):923-5. doi: 10.1136/pgmj.66.781.923.
Liver involvement in typhoid fever is uncommon. Typhoid hepatitis is now being recognized as a definite entity. Over a period of 4 years, we have observed 10 cases (4.8%) of typhoid hepatitis out of 210 cases of typhoid fever. Jaundice, anaemia, hepatomegaly and abnormal biochemical tests were present in all cases. Liver biopsy was done in 8 cases and was found to be abnormal in 5. Two of the 10 cases of typhoid hepatitis died. Recognition of typhoid hepatitis is important since it has to be differentiated from other common ailments in the tropics such as viral, malarial or amoebic hepatitis. Early institution of specific therapy in cases of typhoid hepatitis carries a good prognosis.
伤寒热累及肝脏的情况并不常见。伤寒性肝炎如今已被确认为一种明确的病症。在4年时间里,我们在210例伤寒热病例中观察到10例(4.8%)伤寒性肝炎。所有病例均出现黄疸、贫血、肝肿大及生化检查异常。对8例进行了肝脏活检,其中5例结果异常。10例伤寒性肝炎病例中有2例死亡。认识到伤寒性肝炎很重要,因为它必须与热带地区其他常见疾病如病毒性、疟疾性或阿米巴性肝炎相鉴别。伤寒性肝炎病例早期采用特异性治疗预后良好。