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职业性氰化物中毒

Occupational cyanide poisoning.

作者信息

Amizet Loic, Pruvot Gauthier, Remy Sophie, Kfoury Michel

机构信息

Service des Urgences SAU/SMUR, College de Medecine d'Urgence de Picardie, Abbeville, France.

出版信息

BMJ Case Rep. 2011 Nov 21;2011:bcr0920114865. doi: 10.1136/bcr.09.2011.4865.

DOI:10.1136/bcr.09.2011.4865
PMID:22674698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3229413/
Abstract

Cyanide poisoning has existed for centuries. In most cases, cyanide is combined with other toxic substances; for example with carbon monoxide in fire smoke. Cases of pure cyanide poisoning are rare, and usually due to accidental exposure. Their treatment is based on oxygenation and the infusion of hydroxocobalamin. The seriousness of this type of poisoning calls for a rapid and specific response, which demonstrates the usefulness of non-hospital based medical treatment. The authors report here the case of a man who was the victim of occupational poisoning with sodium cyanide and who was treated at the workplace by fire-fighters and the Service Mobile d'Urgence et Reanimation emergency ambulance service.

摘要

氰化物中毒已存在数百年。在大多数情况下,氰化物与其他有毒物质结合;例如在火灾烟雾中与一氧化碳结合。纯氰化物中毒的病例很少见,通常是由于意外接触。其治疗基于氧合作用和羟钴胺素的输注。这类中毒的严重性需要迅速而特定的应对措施,这表明了非医院基础医疗治疗的有用性。作者在此报告一例职业性氰化钠中毒男性病例,该患者在工作场所由消防员和紧急医疗救护服务移动急救队进行了治疗。

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本文引用的文献

1
Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study.在一项随机、安慰剂对照研究中,健康志愿者使用羟钴胺素的安全性。
Clin Toxicol (Phila). 2006;44 Suppl 1:17-28. doi: 10.1080/15563650600811755.
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Cyanide poisoning: pathophysiology and treatment recommendations.氰化物中毒:病理生理学及治疗建议
Occup Med (Lond). 1998 Oct;48(7):427-31. doi: 10.1093/occmed/48.7.427.