Heath A C, Kendler K S, Eaves L J, Martin N G
Department of Human Genetics, Medical College of Virginia, Richmond.
Sleep. 1990 Aug;13(4):318-35. doi: 10.1093/sleep/13.4.318.
The etiologic role of genotype and environment in sleep pattern (daytime napping, habitual bedtime, and sleep duration) and subjective sleep quality and sleep disturbance was examined using a general population sample of 3,810 adult Australian twin pairs, aged 17-88 years. Genetic differences accounted for at least 33% of the variance in sleep quality and sleep disturbance and 40% of the variance in sleep pattern. There was no evidence for a decline in the importance of genetic predisposition with age. Short-term environmental fluctuations accounted for as much as 30% of the variance, and more stable nonfamilial environmental effects accounted for the remainder. No effect of shared family environment on sleep characteristics was found.
利用3810对年龄在17 - 88岁的澳大利亚成年双胞胎组成的一般人群样本，研究了基因型和环境在睡眠模式（白天小睡、习惯性就寝时间和睡眠时间）以及主观睡眠质量和睡眠障碍中的病因学作用。遗传差异至少占睡眠质量和睡眠障碍方差的33%，以及睡眠模式方差的40%。没有证据表明遗传易感性的重要性会随着年龄增长而下降。短期环境波动占方差的比例高达30%，更稳定的非家庭环境影响占其余部分。未发现共享家庭环境对睡眠特征有影响。
