Carney Centre for Pharmacogenomics & Department of Pathology, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.
Pharmacogenomics. 2012 Jun;13(8):865-8. doi: 10.2217/pgs.12.55.
The integration of genetics and genomics with pharmacology and clinical medicine has enriched our understanding of all of these disciplines and is steadily providing a more complete picture of the etiology, pathophysiology and treatment of disease. To capitalize on this new knowledge requires the ability to evaluate the underlying evidence base and to test the utility of any proposed pharmacogenetic or genomic approaches to personalized medicine, within local or regional healthcare structures. The Carney Centre for Pharmacogenomics is now in its eighth year of operation, and although small by international standards, it has proven to be a valuable focus for research, training and dissemination of such knowledge in New Zealand and beyond. By focusing predominantly on research and training, the center has raised awareness about the value and limitations of pharmacogenetics and pharmacogenomic approaches.
遗传学和基因组学与药理学和临床医学的结合丰富了我们对所有这些学科的理解,并为疾病的病因、病理生理学和治疗提供了更完整的图景。要利用这些新知识,就需要有能力评估潜在的证据基础,并在当地或区域医疗保健结构内测试任何拟议的药物遗传学或基因组学方法在个性化医疗中的实用性。卡尼药物基因组学中心已经运营了八年,虽然按照国际标准规模较小,但它已被证明是新西兰及其他地区开展此类研究、培训和知识传播的一个有价值的中心。该中心主要侧重于研究和培训,提高了人们对药物遗传学和药物基因组学方法的价值和局限性的认识。