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[滨海边疆区和远东地区多发性硬化症的流行病学]

[Epidemiology of multiple sclerosis in the Primosky Krai and Far East regions].

作者信息

Gavrilenko A A, Evdokimova Z S, Vasikovskaia G A, Boĭko A N

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2012;112(2 Pt 2):5-8.

Abstract

The first results of a clinical and epidemiological survey on prevalence, incidence, clinical characteristics, diagnosis of multiple sclerosis (MS) and medical assistance to patients in Primosky Krai, Vladivostok and the Far East regions (Sakhalin, Magadan oblasts and Kamchatka Krai) during 2005-2010 are presented. The prevalence of MS was 1.12 cases per 100000 population in the Primosky Krai in whole and from 1.61 cases in 2005 in Vladivostok to 11.45 and 16.2 cases in Primosky Krai and Vladivostok in 2010, respectively. The incidence of MS was maximal in the Primosky Krai (2.61 cases per 100 000 population in 2007 and 3.95 cases in 2008). The increase in the prevalence may be explained by the improvement of MS diagnosis, introduction of neuroimaging methods for brain structure visualization (MRI etc) and the organization of a regional MS center. The relative decrease in the MS incidence to 2.49 cases per 100 000 in 2010 was noted. Epidemiological characteristics of MS in separate oblasts of the Far East are presented. In whole, all indices indicate the moderate risk for MS in the region studied.

摘要

本文呈现了2005 - 2010年期间,对滨海边疆区、符拉迪沃斯托克以及远东地区(萨哈林州、马加丹州和堪察加边疆区)多发性硬化症(MS)的患病率、发病率、临床特征、诊断情况以及患者医疗救助情况进行的临床和流行病学调查的初步结果。滨海边疆区MS的总体患病率为每10万人口1.12例,符拉迪沃斯托克的患病率从2005年的1.61例,分别增至2010年滨海边疆区的11.45例和符拉迪沃斯托克的16.2例。MS发病率在滨海边疆区最高(2007年为每10万人口2.61例,2008年为3.95例)。患病率的增加可能是由于MS诊断水平的提高、用于脑结构可视化的神经影像学方法(如MRI等)的引入以及地区MS中心的设立。2010年MS发病率相对降至每10万人口2.49例。文中还呈现了远东地区各单独州MS的流行病学特征。总体而言,所有指标表明所研究地区MS的风险为中度。

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