Department of Oral Diagnosis and Dentomaxillofacial Radiology, Okayama University Hospital, Okayama, Japan.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Jan;113(1):118-25. doi: 10.1016/j.tripleo.2011.06.038. Epub 2011 Oct 8.
High-dose-rate (HDR) brachytherapy using a customized mold is a minimally invasive treatment for oral cancer; however, it is difficult to use this technique for buccal and lip cancers involving the commissura labiorum, owing to its anatomic form. The purpose of this study was to introduce an improved customized mold consisting of 2 pieces to allow the fixation of molds to these sites.
Five patients with buccal carcinoma and 1 patient with lip carcinoma were treated with this technique after external beam radiotherapy. One patient with neck metastasis underwent both neck dissection and partial tumor resection before HDR brachytherapy.
At the end of the follow-up period, 5 patients had no tumor recurrence, and 1 patient had suffered local recurrence.
Our technique is a viable therapeutic option for patients with buccal and lip carcinomas for whom the therapeutic modalities are limited by age, performance status, and other factors.
使用定制模具的高剂量率（HDR）近距离放疗是治疗口腔癌的一种微创方法；然而，由于其解剖形态，对于涉及口角的颊部和唇部癌症，很难使用这种技术。本研究的目的是介绍一种由 2 部分组成的改良定制模具，以固定这些部位的模具。
5 例颊部癌患者和 1 例唇癌患者在外照射放疗后接受了这种技术治疗。1 例颈部转移患者在 HDR 近距离放疗前接受了颈清扫术和部分肿瘤切除术。
在随访期末，5 例患者无肿瘤复发，1 例患者发生局部复发。
对于因年龄、身体状况和其他因素而治疗方法受限的颊部和唇部癌症患者，我们的技术是一种可行的治疗选择。
