Walloon Excellence in Life Science and Biotechnology, Interdisciplinary Research Institute, Université Libre de Bruxelles, 808, route de Lennik, BatC, C6-130, 1070 Brussels, Belgium.
Nat Rev Mol Cell Biol. 2012 Jun 8;13(7):471-6. doi: 10.1038/nrm3371.
The increasing momentum of stem cell research continues, with the better characterization of induced pluripotent stem (iPS) cells, the conversion of differentiated cells into different cell types and the use of pluripotent stem cells to generate whole tissues, among other advances. Here, six experts in the field of stem cell research compare different stem cell models and highlight the importance of pursuing complementary experimental approaches for a better understanding of pluripotency and differentiation and an informed approach to medical applications.
干细胞研究的势头不断增强，其中包括更好地表征诱导多能干细胞 (iPS) 细胞、将分化细胞转化为不同细胞类型以及利用多能干细胞生成整个组织等进展。在这里，六位干细胞研究领域的专家比较了不同的干细胞模型，并强调了追求互补实验方法的重要性，以更好地理解多能性和分化，并为医学应用提供明智的方法。
