Shvyrkov M B
Stomatologiia (Mosk). 2012;91(1):9-12.
Influents of some medicines on the mandible reparative regeneration in experimental investigations are present in the manuscript. It was discovered that application of parathyroid hormone (PTG) in first 3 days after the mandible fracture decreases of quantity complications on 30% and contributes strong consolidation of bone fragments. Metiluracil in the same period increases complications quantity on 36% and bone fragments consolidation strength was for sure less than after PTG. It was found PTG and vitamin D3 in first resorbtion stage accelerate bone consolidation, retabolil (nandrolone), dexametasone, testosterone and vitamin E slow down bone consolidation. Role of vitamin A, indometazin and calcitonin was doubtful. Practical doctors and experimenters co-ordination efforts are necessary for elaboration of new tactic and strategy of patient treatment with bone trauma.
手稿中呈现了一些药物在实验研究中对下颌骨修复性再生的影响。研究发现，在下颌骨骨折后的前3天应用甲状旁腺激素（PTG）可使并发症数量减少30%，并有助于骨碎片的牢固愈合。同期的甲硫尿嘧啶会使并发症数量增加36%，且骨碎片的愈合强度肯定低于PTG治疗后。研究发现，在最初的吸收阶段，PTG和维生素D3可加速骨愈合，康复龙（诺龙）、地塞米松、睾酮和维生素E则会减缓骨愈合。维生素A、吲哚美辛和降钙素的作用尚不确定。为制定骨创伤患者治疗的新策略和新方法，临床医生和实验人员有必要共同努力。
