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严重的克里米亚-刚果出血热表现为大量腹膜后出血,未经抗病毒治疗即康复。

Severe Crimean-Congo haemorrhagic fever presented with massive retroperitoneal haemorrhage that recovered without antiviral treatment.

作者信息

Gharabaghi Mehrnaz Asadi, Chinikar Sadegh, Ghiasi Seyyed Mojtaba, Morady Maryam, Ahmadinejhad Taha, Paydary Koosha

机构信息

Department of Medicine, Imam Khomeini hospital complex, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

BMJ Case Rep. 2011 Aug 19;2011:bcr1020103408. doi: 10.1136/bcr.10.2010.3408.

Abstract

Crimean-Congo haemorrhagic fever (CCHF) is a tickborne viral zoonosis with up to 50% mortality in humans caused by CCHF virus belonging to the genus Nairovirus, family Bunyaviridae. The geographical distribution of CCHF cases corresponds closely with the distribution of principle tick vectors that is species of Hyaloma. The disease presents with non-specific febrile symptoms, but progress to a serious haemorrhagic syndrome that, soon after, a full blown multi organ failure may develop with prominent features of liver damage and bleeding diathesis. The authors present a case of a 39-year-old man with severe CCHF with retroperitoneal haemorrhage that recovered without ribavirin administration. The case was confirmed for CCHF by serological and molecular tests.

摘要

克里米亚-刚果出血热(CCHF)是一种由属于布尼亚病毒科内罗病毒属的CCHF病毒引起的蜱传病毒性人畜共患病,在人类中的死亡率高达50%。CCHF病例的地理分布与主要蜱虫传播媒介(即璃眼蜱属物种)的分布密切相关。该疾病最初表现为非特异性发热症状,但随后会发展为严重的出血综合征,不久后可能会出现全面的多器官功能衰竭,并伴有肝损伤和出血素质的显著特征。作者报告了一例39岁患有严重CCHF并伴有腹膜后出血的男性病例,该患者未接受利巴韦林治疗却康复了。该病例通过血清学和分子检测确诊为CCHF。

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