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术前偶然发现心电图显示Brugada表型的困境。

The dilemma of an incidental preoperative electrocardiogram showing a Brugada phenotype.

作者信息

Welman Kiera, Matloob Samir, Dubrey Simon William, Elliott Perry

机构信息

Cardiology Department, Hillingdon Hospital, Uxbridge, Middlesex, UK.

出版信息

BMJ Case Rep. 2011 Aug 31;2011:bcr0620114418. doi: 10.1136/bcr.06.2011.4418.

DOI:10.1136/bcr.06.2011.4418
PMID:22679049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3176352/
Abstract

A Brugada pattern on routine electrocardiography is one of several features that can indicate the potential for life threatening rhythm disturbances. The authors describe such a scenario in an asymptomatic 38-year-old woman who required significant surgery under anaesthesia. The diagnosis and possible management routes are outlined with an emphasis on the incumbent psychosocial and familial issues that are encountered. The patient underwent her surgery and was then further investigated to 'prove' the diagnosis. Ultimately, the patient declined further investigations and interventions. This case highlights the dilemma faced by anaesthetists and clinicians, not to mention the patients and their family when a Brugada phenotype is identified on a routine ECG. Clinicians should seek an expert opinion but ultimately, as in this case, the patient should be positioned to make an informed decision on what route to follow.

摘要

常规心电图上的Brugada波型是提示潜在危及生命的心律失常可能性的几种特征之一。作者描述了一名38岁无症状女性的此类情况,该女性需要在麻醉下进行重大手术。文中概述了诊断及可能的处理途径,重点强调了所遇到的相关社会心理和家庭问题。患者接受了手术,随后进行了进一步检查以“证实”诊断。最终,患者拒绝了进一步检查和干预。该病例凸显了麻醉医生和临床医生所面临的困境,更不用说当在常规心电图上识别出Brugada表型时患者及其家人所面临的困境了。临床医生应寻求专家意见,但最终,就像在这个病例中一样,应让患者能够在后续采取何种途径方面做出明智的决定。

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Saudi J Anaesth. 2023 Jul-Sep;17(3):394-400. doi: 10.4103/sja.sja_205_23. Epub 2023 Jun 22.

本文引用的文献

1
Long-term prognosis of patients diagnosed with Brugada syndrome: Results from the FINGER Brugada Syndrome Registry.Brugada 综合征患者的长期预后:FINGER Brugada 综合征注册研究结果。
Circulation. 2010 Feb 9;121(5):635-43. doi: 10.1161/CIRCULATIONAHA.109.887026. Epub 2010 Jan 25.
2
Drugs and Brugada syndrome patients: review of the literature, recommendations, and an up-to-date website (www.brugadadrugs.org).药物与 Brugada 综合征患者:文献回顾、建议和最新网站(www.brugadadrugs.org)。
Heart Rhythm. 2009 Sep;6(9):1335-41. doi: 10.1016/j.hrthm.2009.07.002. Epub 2009 Jul 8.
3
Electrocardiogram interpretation and class I blocker challenge in Brugada syndrome.Brugada综合征的心电图解读与I类阻滞剂激发试验
J Electrocardiol. 2006 Oct;39(4 Suppl):S115-8. doi: 10.1016/j.jelectrocard.2006.05.014. Epub 2006 Aug 28.
4
Value of electrocardiographic parameters and ajmaline test in the diagnosis of Brugada syndrome caused by SCN5A mutations.心电图参数及阿义马林试验在诊断SCN5A基因突变所致Brugada综合征中的价值
Circulation. 2004 Nov 9;110(19):3023-7. doi: 10.1161/01.CIR.0000144299.17008.07. Epub 2004 Nov 1.