de Vasquez A M, Saenz R E, Petersen J L, Christensen H A, Johnson C M
Gorgas Memorial Laboratory, Panama.
Am J Trop Med Hyg. 1990 Dec;43(6):619-22. doi: 10.4269/ajtmh.1990.43.619.
Parasites of the genus Leishmania responsible for human cutaneous leishmaniasis in the New World form 2 major taxonomic divisions: the Leishmania braziliensis and the L. mexicana complexes. We report the isolation and characterization of the L. mexicana complex among humans in the Republic of Panama. Characterization was based on parasite morphology, pathogenesis in infected golden hamsters, cellulose acetate isoenzyme electrophoretic mobilities, and membrane-specific monoclonal antibodies using the radioimmune binding assay technique.
在新大陆导致人类皮肤利什曼病的利什曼原虫属寄生虫形成了2个主要的分类学分支：巴西利什曼原虫和墨西哥利什曼原虫复合体。我们报告了在巴拿马共和国人群中分离和鉴定墨西哥利什曼原虫复合体的情况。鉴定基于寄生虫形态、在感染金黄仓鼠中的致病机制、醋酸纤维素同工酶电泳迁移率以及使用放射免疫结合测定技术的膜特异性单克隆抗体。
