NMDA 受体协同检测是否是学习和记忆所必需的？
Is NMDA receptor-coincidence detection required for learning and memory?
机构信息
Trinity College Institute for Neuroscience, Ireland.
出版信息
Neuron. 2012 Jun 7;74(5):767-9. doi: 10.1016/j.neuron.2012.05.008.
PMID:22681680
Abstract
The Mg2+ block of NMDA-type glutamate receptors (NMDARs) is crucial to their function as synaptic coincidence detectors. An analysis of Drosophila expressing a Mg2+-independent NMDAR by in this issue of Neuron concludes that the Mg2+ block is required primarily for long-term memory.
摘要
该 Mg2+ 阻断 NMDA 型谷氨酸受体 (NMDAR) 是它们作为突触符合探测器功能的关键。神经元杂志本期发表的一篇文章对表达一种 Mg2+ 非依赖性 NMDAR 的果蝇进行了分析，得出的结论是，Mg2+ 阻断主要是为了长期记忆。
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