相似文献
1
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors.
Structure. 2012 Jun 6;20(6):967-76. doi: 10.1016/j.str.2012.04.010.
2
N-terminal T4 lysozyme fusion facilitates crystallization of a G protein coupled receptor.
PLoS One. 2012;7(10):e46039. doi: 10.1371/journal.pone.0046039. Epub 2012 Oct 4.
3
Purification and Crystallization of a Thermostabilized Agonist-Bound Conformation of the Human Adenosine A(2A) Receptor.
Methods Mol Biol. 2015;1335:17-27. doi: 10.1007/978-1-4939-2914-6_2.
4
State-Targeting Stabilization of Adenosine A Receptor by Fusing a Custom-Made De Novo Designed α-Helical Protein.
Int J Mol Sci. 2021 Nov 29;22(23):12906. doi: 10.3390/ijms222312906.
5
Crystallization of G protein-coupled receptors.
Methods Cell Biol. 2013;117:451-68. doi: 10.1016/B978-0-12-408143-7.00024-4.
6
Structural basis for allosteric regulation of GPCRs by sodium ions.
Science. 2012 Jul 13;337(6091):232-6. doi: 10.1126/science.1219218.
7
Functional fusions of T4 lysozyme in the third intracellular loop of a G protein-coupled receptor identified by a random screening approach in yeast.
Protein Eng Des Sel. 2013 Jan;26(1):59-71. doi: 10.1093/protein/gzs070. Epub 2012 Oct 16.
8
GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.
Science. 2007 Nov 23;318(5854):1266-73. doi: 10.1126/science.1150609. Epub 2007 Oct 25.
9
Crystallogenesis of adenosine A(2A) receptor-T4 lysozyme fusion protein: a practical route for the structure.
Methods Enzymol. 2013;520:175-98. doi: 10.1016/B978-0-12-391861-1.00008-3.
10
Production of functional recombinant G-protein coupled receptors for heteromerization studies.
J Neurosci Methods. 2011 Aug 15;199(2):258-64. doi: 10.1016/j.jneumeth.2011.05.021. Epub 2011 May 31.
引用本文的文献
1
Decoding ligand recognition and constitutive activation of histamine H3 and H4 receptors.
Acta Pharmacol Sin. 2025 Aug 28. doi: 10.1038/s41401-025-01633-4.
2
Crystal structures of agonist-bound human cannabinoid receptor CB.
Nature. 2025 Aug 27. doi: 10.1038/s41586-025-09454-5.
3
Mechanistic insights into the versatile stoichiometry and biased signaling of the apelin receptor-arrestin complex.
Nat Commun. 2025 Aug 11;16(1):7403. doi: 10.1038/s41467-025-62870-z.
4
Optimization of the prostaglandin F2α receptor for structural biology.
PLoS One. 2025 Jul 18;20(7):e0320114. doi: 10.1371/journal.pone.0320114. eCollection 2025.
5
Assembly and activation of the death-inducing signaling complex.
Proc Natl Acad Sci U S A. 2025 Jun 10;122(23):e2504819122. doi: 10.1073/pnas.2504819122. Epub 2025 Jun 4.
6
Preparing for successful protein crystallization experiments.
Acta Crystallogr F Struct Biol Commun. 2025 Jul 1;81(Pt 7):272-280. doi: 10.1107/S2053230X25004650. Epub 2025 Jun 2.
7
Molecular basis for ligand recognition and receptor activation of the prostaglandin D2 receptor DP1.
Proc Natl Acad Sci U S A. 2025 Jun 3;122(22):e2501902122. doi: 10.1073/pnas.2501902122. Epub 2025 May 29.
8
Structural insights into the activation of the human prostaglandin E receptor EP1 subtype by prostaglandin E.
Proc Natl Acad Sci U S A. 2025 May 20;122(20):e2423840122. doi: 10.1073/pnas.2423840122. Epub 2025 May 14.
9
Unlocking GPCR-ligand interactions: Measuring binding affinities with thermal shift assay.
Protein Sci. 2025 May;34(5):e70120. doi: 10.1002/pro.70120.
10
Ion-conducting and gating molecular mechanisms of channelrhodopsin revealed by true-atomic-resolution structures of open and closed states.
Nat Struct Mol Biol. 2025 Apr 9. doi: 10.1038/s41594-025-01488-7.
本文引用的文献
1
Structural basis for allosteric regulation of GPCRs by sodium ions.
Science. 2012 Jul 13;337(6091):232-6. doi: 10.1126/science.1219218.
2
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic.
Nature. 2012 May 16;485(7398):395-9. doi: 10.1038/nature11085.
3
Structure of the human κ-opioid receptor in complex with JDTic.
Nature. 2012 Mar 21;485(7398):327-32. doi: 10.1038/nature10939.
4
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist.
Nature. 2012 Mar 21;485(7398):321-6. doi: 10.1038/nature10954.
5
Structure and dynamics of the M3 muscarinic acetylcholine receptor.
Nature. 2012 Feb 22;482(7386):552-6. doi: 10.1038/nature10867.
6
Crystal structure of a lipid G protein-coupled receptor.
Science. 2012 Feb 17;335(6070):851-5. doi: 10.1126/science.1215904.
7
G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody.
Nature. 2012 Jan 29;482(7384):237-40. doi: 10.1038/nature10750.
8
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.
Nature. 2012 Jan 25;482(7386):547-51. doi: 10.1038/nature10753.
9
Engineering an ultra-thermostable β(1)-adrenoceptor.
J Mol Biol. 2011 Oct 28;413(3):628-38. doi: 10.1016/j.jmb.2011.08.057. Epub 2011 Sep 6.
10
Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX.
Structure. 2011 Oct 12;19(10):1424-32. doi: 10.1016/j.str.2011.08.001. Epub 2011 Sep 1.
Zotero 插件